| Obect i ve:Bronchial asthma is a traditional Chinese medicine,"Asthma" category, the Chinese believe whooping disease pathological factors, mainly in sputum, is an attack of phlegm asthma disorders, and on the basis of dysfunctional organs, be added Six Exogenous diet section, emotional excesses, over-exerting, and other factors induced. Sputum volts induced in the lung, the case of evils lead to Asthma. Doctors believe that participation by a large number of eosinophilic granulocytes, mast cells and T lymphocytes (Th2) and other inflammatory cells, airway epithelial cells, airway chronic allergic inflammatory disease. Its main feature is airway hyperresponsiveness, airway inflammation is the main factor to cause airway hyperresponsiveness, infiltration of eosinophils (EOS) is one of the characteristics of asthma. The main subject of the group (taking the flavored Dingchuan soup) with the control group (taking cough tablets) treatment of bronchial asthma with acute exacerbation of (cold beam table, phlegm resistance card) set, and its symptoms, signs overall performance, as well as points of Chinese medicine the main symptoms of the disease, pulmonary function, PaO2, and PaC02, the EOS count of IgE determination and sputum volume changes in the clinical observation, analysis and research.Methods:Selected50cases (clinically diagnosed with acute exacerbation of bronchial asthma, TCM is a cold beam, phlegm internal resistance syndrome) patients, all belonging to Hubei Province, Chinese medicine hospital respiratory medicine clinic patients were randomly divided into treatment group of25cases25cases and the control group, gender, age, severity of disease, Chinese medicine, the main disease, and sub-syndrome integration of two groups of patients before treatment, pulmonary function, PaO2, and PaC02, the EOS count of IgE determination and sputum volume changes were statistically deal with no significant difference (P>0.05) were comparable. Treatment group to be the flavored Dingchuantang (ephedra15g, cicada slough10g, the ginkgo10g, Perilla10g, Coltsfoot10g, Almond10g, Cortex Mori10g skullcap10g, the10g of Pinellia, Poria10g, licorice root6g, water decoction, day one, each agent End of2times service, each200ml) treatment, the control group to be Chuankening film (production by the Harbin Teva Pharmaceutical Co., Ltd., the State Yaozhun Z23022125, the main component of Campanulaceae143g pig bile38g,143g licorice, bitter almond cream38g, the ephedra214g, oral, once four, three times a day) treatment, both groups are one week for a course, after taking two courses were observed before and after treatment symptoms, signs performance and lung function, the value of peak velocity, arterial blood gas analysis, the EOS count of IgE determination and sputum volume changes, and compare its efficacy.ResuIts:After this project the observed results showed that72%of the total effective rate of the treatment group (the administration flavored Dingchuantang) the total effective rate of92%in the control group (administration Chuankening film). Two groups of patients with total efficiency (P<0.05) by statistical analysis that suggest that treatment results are significant differences. The treatment group and control group of disease and disease score total efficiency of96%and72%, respectively, after statistical analysis(P<0.05)significant difference. Sputum volume improvement in the two groups of patients before and after treatment were significant differences (P<0.05); improvement of FEV1and IgE determination by statistical analysis (P<0.01), more obvious differences in the treatment group is definitely better than the control group; PEF, FVC and the PaO2and PaC02, the EOS count to improve a significant difference (P<0.05), the results show that the treatment group than the control group.Conclusion:In this study, gas, in TCM Xuanfei drop the phlegm governance on the basis of TCM V sputum stop build with internal pulmonary orifices, the treatment group to give the flavored Dingchuantang, its main effect for heat Xuanfei the phlegm Dingchuan and by suppressing anti-inflammatory, so bronchodilator, airway patency, plays a vital role in the treatment of bronchial asthma. Control group to give piece Chuankening, its main effect is cough and asthma, and is used within known as the heat outside but also feel the cold-induced cough disease. Two groups of patients are also taking a selected drug, but patients treated with the improvement in symptoms than the control group, the patients with acute exacerbation of bronchial asthma the flavored Dingchuan soup has certain advantages in the clinical efficacy than Chuankening tablet. |
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