Efficacy Evaluation Of Acupoint Application Of Chinese Medicine In Treating Chronic Functional Constipation

Objective:To evaluate the efficacy and safety of Acupoint application of Chinese Medicine for chronic functional constipationMethods:the methods of self controlled study before and after design was adopted in the trial, Patients who with chronic functional constipation were divided into before treatment and after treatment, the two groups. Acupoint will be paste Shenque, Tianshu, Guanyuan, Dachangshu, Pishu, fixed with adhesive tape. Day1, every5-6hours, seven times for one course.Results:Among67included cases,.the primary outcome was the score of main symptoms of real hot constipation. The secondary outcomes were the score of minor symptoms of real hot constipation, defecate frequency in7days, duration of start efficacy. Safety evaluation included adverse events and related laboratory tests. The results were as follow.The primary outcome,(1) the main symptom integral improvement. Treatment for7days,7days after stopping points score was5.31±3.68,9.27±3.454,(2) secondary efficacy parameters,1) symptoms integral improvement. For7days, integral, and7days after stopping points were2.48±1.19,2.22±0.93.2)7days defecation frequency. Before treatments days of integral, integral treatment and7days after stopping points werel.99±0.91,4.03±1.56,4.10±1.29,3) each average defecation time (min):before the treatment time, treatment for7days, and7days after stopping time were20.45±7.55,15.09±7.42,18.69±6.07.4) attached to the first defecation time. Sticking to the first defecation time was23.25±14.59hours,(3) total score improvement: before treatment integral, integral, for7days and7days after stopping points were20.73±6.33,7.79±4.04,12.49±3.46(4): efficiency of Acupoint Application of Chinese medicine treatment of CFC total efficiency for82.08%, of which7cases were clinically controlled, accounted for10.44%,19cases were markedly effective,28.35%, improvement in17cases, accounting for25.37%.Conclusion:acupoint sticking can improve the symptoms of CFC (Yang deficiency) patients with dry stool, difficult to pass, abdominal distension and increase defecate frequency in7days. It was an effective and safe agent in the treatment of chronic functional constipation.