Invigorating Spleen And Tonifying Kidney And Removing Blood Stasis And Phlegm In Chronic Renal Failure With Coronary Heart Disease And Serum Monoamine Oxidase Effect

Objective:This research by strengthening spleen and kidney, removing blood stasis and phlegm with self-made Decoction in treatment of chronic renal failure complicated with coronary heart disease observation of serum monoamine oxidase changes, and traditional Chinese medicine treatment of chronic renal failure with coronary artery disease.Monoamine oxidase is found mainly in heart. Renal. Liver and other organs of the connective tissues and mitochondria of soluble enzymes, the enzymes involved in the immature collagen fibers at the final stage of bridging process, accelerate tissue fibrosis.Serum monoamine oxidase activity can reflect indirectly the heart and kidney tissue damage degree and hyperplasia of fibrous tissue, this enzyme determination in chronic renal failure patients with coronary artery disease complicated with heart kidney injury status with clinical significance of monitoring.Methods:The study of chronic renal failure complicated with coronary heart disease of spleen kidney two empty, phlegm and blood stasis syndrome in40cases of patients with block, based on the use of. treatment include primary disease and treatment of predisposing factors, diet, rest, control of hypertension, correct water, electrolyte disturbance and acid-base balance disorders, infection control, relief of anginal episodes, as well as other treatments.On the basis of treatment on the basis of strengthening spleen and kidney, removing blood stasis and phlegm method in TCM Decoction, a month is a treatment course, after two courses of therapeutic efficacy, were observed before and after treatment in patients with coronary artery disease complicated with chronic renal failure syndrome changes, observation of serum monoamine oxidase changes, and detection of electrocardiogram before and after the treatment, the liver function, renal, ion, lipid changes of indexes.Results:1.The overall clinical efficacy before and after treatment with statistical significance (P<0.05), after treatment of patients with symptoms and to improve significantly better than before treatment (P<0.01).2.Before and after treatment, serum monoamine oxidase was significantly reduced, with statistical significance (P<0.01), ECG, renal function, blood lipids were significantly improved, with statistical significance (P<0.05).Conclusion:1.strengthening spleen and kidney, removing blood stasis and phlegm method to reduce chronic renal failure complicated with coronary heart disease with TCM Symptom integral, improve the patient’s ymptoms.2.strengthening spleen and kidney, removing blood stasis and phlegm can obviously reduce the chronic renal failure patients with coronary heart disease and serum monoamine oxidase, delaying chronic renal failure with the progression of coronary heart disease.3.strengthening spleen and kidney, removing blood stasis and phlegm method can improve the patients ECG, renal function, blood lipid levels.