| Objective:To study the causes of psoriasis pustular hairstyle and contributing factors, clinical manifestation, related laboratory examination and treatment.Methods:Methods:collect qilu hospital of shandong university dermatologist2005～2012of hospitalization in53GPP medical records of patients, the disease of the factors, clinical manifestations, treatment, laboratory examination were retrospectively analyzed, with the aid of computer SPSS17.0software, application t test, chi-square, linear correlation analysis on the clinical data of statistical analysis.Results:(1) Gender, age of onset:53cases. The actual patients for42people, there are11people because of the disease recurrent several times and hospital (2～4times). Male22people, female20people, male:female=1.1:1, with an average age of27.98±17.6years old (2to65years); PSO-patients with psoriasis pustular occurred first type age24.7±14.87years old, PSO+patients with psoriasis pustular occurred first type the age of35.75±15.65years old, both comparing statistical significance (p<0.01);(2) Come on incentives and season with clear the incentives of37patients (69.8%), have the upper respiratory tract infection history14cases (26.5%), improper use9cases (17.0%); Life events in5patients (9.4%); Trauma in5patients (9.4%), endocrine factors in4(7.5%); No significant incentives of16cases (30.2%). Merger of infection in14cases GPP patients and no clear trigger of the16cases of GPP admission with body temperature, WBC count and pustules subsidise time comparing statistical significance;37patients (69.8%) cases occur in spring winter’s day, the more than16cases (30.2%) cases occur in summer and autumn;(3) Clinical manifestations of the whole body rises suddenly pustules in14cases, skin rash new-onset head in facial6cases in11of the limbs, the trunk of17cases, drape part4cases, have1case in point up (toe); The whole body hair more than skin rash, for the size of the tip pustular, part (41.5%) merge into "pus lake". Pustular appeared in20patients with psoriasis vulgaris lesions, appears in the normal skin20cases, erythematous base in3,10cases of children of the patients presented to normal skin or erythematous base;19patients (35.8%) were admitted to the hospital patients have skin tenderness;6patients (11.3%) patients experienced joint acid bilges, pain symptoms. Ditch grain tongue8cases (15.1%);(4) Laboratory tests pustular type patients with psoriasis and WBC, N%and serum calcium, serum albumin, total protein comparative differences before and after treatment with a statistical significance;(5) treatment Various combinations of drugs pustular retreat at different timesConclusion:(1) the hairstyle pustular type psoriasis can happen at any age, the men and women all suffer from, and pso-age of onset of GPP than pso+GPP early;(2) pustular type psoriasis good hair at spring winter’s day; There are a variety of inducing factors, especially in infection factors common and can aggravating illness, treatment given antibiotics to illness recovery;(3) WBC count, serum calcium and albumin can be used as evaluating the important reference index of and prognosis;(4) at present A and MTX still above for GPP first-line use, the preferred above A, serious illness can drink the joint use of corticosteroids, kind of hormone drugs, etc. |
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