The Microecological Evaluation And Clinical Characteristics Of Aerobic Vaginitis

Objective: Evaluate the microecological situation (by analysis ofvaginal flora, Lactobacillus count, vaginal pH value changes) of aerobicvagitis(AV), thus provide help for prevention, treatment and prognosis inAV patients. And discuss the clinical characteristics of aerobic vaginitis andits associated with bacterial vaginosis(BV), vulvovaginal candidiasis(VVC),trichomoniasis vaginitis(TV) of mixed infections, in order to furtherimprove the clinician for aerobic vaginitis understanding.Methods: From July2011to December2011in the Second AffiliatedHospital of Chongqing Medical University Department of Gynecology andObstetrics laboratory examination of vaginal secretions in the1948patientscases, collected vaginal secretions, with AV/BV Diagnostic Strip Sets fordetermination of aerobic vaginitis, and analysis the vaginal flora of AVpatients. Then check vaginal secretions cleanliness, pH value, andobservation of Lactobacillus, trichomonas, Candida, clue cells under oilimmersion lens after Gram staining for evaluate the micro-ecologicalenvironment. And analysis of aerobic vaginitis patients age distribution andclinical characteristics. Results:1. In1948cases, including300cases of aerobic vaginitispatients, it accounted for15.40%(300/1948). And their vaginalmicro-ecological are abnormal state.2.300cases aerobic vaginitis in patients with vaginalmicro-ecological imbalance characteristics, performance for the vaginalflora mainly to aerobic bacteria (Staphylococci aueas, E.coli andEnterococcus faecalis detection rate was99.33%, B.streptococcic(GBS)detection was34%); And with vaginal Lactobacillus in absence ofobvious(82.67%), followed by Lactobacillus reduced(14.00%); And withvaginal pH value increased, mainly to>4.5, especially in the>5.0(49.33%).3. There were184cases of aerobic vaginitis patients with mixedinfection, accounting for61.33%(184/300), AV+BV are most common,accounting for54.89%(101/184); followed by AV+VVC, accounted for26.09%(48/184); then AV+TV, accounting for8.15%(15/184). There are11cases with AV+BV+VVC, accounting for5.98%(11/184); and9cases withAV+BV+TV, accounting for4.89%(9/184).4. These300cases of aerobic vaginitis patients mainly for21~50years female, accounted for89.67%(269/300), and the highest frequencyof infection (37.33%,112/300) was observed at21~30years, followed by31~40years (32%,96/300), then for41~50years (20.33%,61/300).5. All the aerobic vaginitis patients have different degrees of clinical symptoms, the most common symptoms of AV were yellow and thinvaginal discharge(71.43%,35/49), followed by an increase in vaginalsecretions(42.86%,21/49), and accompanied by painful intercourse(28.57%,14/49) or vaginal pruritus(18.37%,9/49).6. Compared with single aerobic vaginitis patients, aerobic vaginitismixed infection, vagina secreta cleanness worse, higher vaginal pH value,Lactobacillus reduced or absent more obvious, these differences werestatistically significant (P <0.005).Conclusion: With the development of discipline, aerobic vaginitis inrecent years have been gradually recognized and valued, this study foundthat all the aerobic vaginitis in patients with vaginal micro-ecologicalabnormal state. And their vaginal micro-ecological imbalance mainly forhigher rate detection with Staphylococcus aureus, Escherichia coli,Streptococcus, Enterococcus faecalis and GBS, while Lactobacillus inabsence of obvious(82.67%), then caused vaginal pH valueincreased(pH>5.0,49.33%). In1948cases, found in aerobic vaginitisincidence rate is high(15.40%), mainly for21~50years female(89.67%),the most common symptoms were yellow and thin vaginal discharge,followed by an increase in vaginal secretions, and accompanied by painfulintercourse or vaginal pruritus. And it is easy to be mixed infection(61.33%), AV+BV are most common(54.89%), followed by AV+VVC (26.09%). Through the vaginal microecological environment examinationand evaluation, understanding the clinical characteristics of aerobicvaginitis and its mixed infection, it’s helpful for the clinician to furtherunderstanding of aerobic vaginitis, improving the level of diagnosis, andprovide evidence for assessment of prognosis.