Effect On Blood Press Control Of Switching From Irbesartan Tablets To A Combined With Traditional Chinese Medicine Intervention In Patients With Hypertension2Level

Purpose: Through the observation of irbesartan combined with traditional Chinesemedicine on hypertension2level of clinical curative effect of treating hypertension withChinese medicine therapy, to validate the clinical efficacy and safety, so as to provide moreeffective treatment regimens in clinical.Method: Selection of Western medicine for the diagnosis of hypertension2level(middle risk group) and TCM syndrome differentiation belong to wind phlegm perturb on thehead and blood stasis block veins road，the patients as subjects, using self contrast methodresearch. All80cases, the first stage: the lifestyle interventions based on the given irbesartan150mg once a day. For the4week of1courses. The second stage: for after the first phase oftreatment of blood pressure higher than140/90mmHg, given the combined with traditionalChinese medicine decoction (Prunella30g, semen raphani20g, Salvia25g, paeonol30g,earthworm15g, abalone50g, white peony root25g, Achyranthes25g) treatment, decoction300ml, twice a day, sooner or later. For the4week of1courses; and then compares the twostages of treatment efficacy. To explore the traditional Chinese medicine on patients withhypertension antihypertensive effect and improve the clinical symptoms of curative effect.Result: The Irbesartan single drug treatment of blood pressure is not reached SiSBP/SiDBP <140/90mmHg treatment goals for patients, conversion of irbesartan combined withtraditional Chinese medicine treatment, SiDBP and SiSBP were further reduced and10.50±0.38mmHg16.21±0.93mmHg (P <0.01),72.4%patients to achieve treatment goals.According to the antihypertensive efficacy evaluation standards, single use of irbesartangroup total effective rate was47.5%, irbesartan combined with Chinese traditional medicinegroup total effective rate was86.2%, the difference was statistically significant (P <0.01),description of irbesartan combined with traditional Chinese medicine is better than that ofsingle with irbesartan was more effective in lowering blood pressure. The clinical symptomsimproved evaluation, based on the score results combined with statistical analysis, the singleuse of irbesartan group in the total efficiency was35%, irbesartan combined with Chinesetraditional medicine group in the total efficiency of84.48%,the difference was statisticallysignificant(P <0.01). That irbesartan combined with traditional Chinese medicine curative effect than a single use of irbesartan group, and in the improvement of the tongue nature,coating on the tongue, pulse condition and other aspects are better than single use ofirbesartan group.Conclusion: Traditional Chinese medicine in treating hypertension antihypertensiveefficacy not only, but also in the improvement of clinical symptoms and the tongue nature,coating on the tongue, pulse condition, is better than medicine, can improve the patientsquality of life, especially notable is, during the treatment phase was not observed inorthostatic hypotension and any adverse reaction of traditional Chinese medicine decoctionand allergy, shows that Chinese medicine treatment tolerated better clinical application, safeand reliable.