The Yang He Decoction For Treatment Of Ankylosing Spondylitis Alpine Blockage Of The Certificate Of Clinical Research

ObjectiveAnkylosing Spondylitis,AS is the sacroiliac joints and spine joints chronic, progressive inflammatory disease mainly autoimmune diseases. More often in young adults, the main damage to the central axis joint, and to varying degrees involving the peripheral joints, internal organs and other organizations. The disease more common in young people, age of onset is usually in the20-30years old, after the age of30and8before the age of onset is rare. Its prevalence in different countries reported for the more common rheumatic. The domestic data show that male to female ratio is about10:1, and foreign data show that men and women close in recent years, the incidence of an upward trend. Various studies have confirmed that the disease is closely associated with HLA-B27and familial aggregation tendency. Ankylosing Spondylitis (AS) are generally not on people’s lives pose a serious threat, but most patients can be significant lower back stiffness, pain, late or even cause spinal stiffness, deformity, severe body movement disorder, so give patients a great deal of pain, seriously affecting the quality of life of patients. No ideal method that can be completely cured, at home and abroad are recognized as a refractory diseaseTreatmentSubjects from2011.03-2012.1in Jiangsu Province Hospital of Rheumatology and the Drum Tower Hospital out-patient, ward collected40cases met the inclusion standards of cases is divided into two groups:treatment group (group A) with the control group (Group B).Group A:the sun and the decoction for treatment of AS. Yang and Tang is a piece of antler, the cultivated land, ephedra, cassia twig, Mustard Seed, Loranthaceae, Woodwardia, centipedes, walnuts and other components. Addition and subtraction:cold winner, Astragalus, papaya, system Sichuan birds; wet winner plus fangchi, barley; pain winner, plus frankincense and myrrh; painful joints stiff re-add the barley, fried Mustard Seed. Shuijianbi day one, two oral. Group B: oral thalidomide daily200mg orally4times. The two groups of treatment time:for one month, a total of two courses.Results1The erythrocyte sedimentation rate after treatment indicators are a good improvement, a significant difference (P=0.02<0.05) in the A group treatment a month, two months after the effect is still apparent and obvious persistent (P<0.01). Group B a little effect, no significant difference (P=0.11>0.05), two months after the effect is obvious (P<0.01).2two groups after treatment C-reactive protein indicators are a good improvement, group A, B, treatment a significant difference (P>0.05), but two months after the curative effect, there are significant differences (P<0.05). Ankylosing spondylitis (AS) is intractable diseases, C-reactive protein targets can not be back to normal, but can be reduced and continued to maintain this level.3The treatment group treatment program one month after the relief of symptoms is poor, compared with before treatment was no significant difference (P>0.05), significant improvement in clinical symptoms after two months, a significant difference compared with before treatment (P<0.05). Control group, one month after treatment, immediately effective, there are significant differences, but after the two treatment effects after one course of treatment no significant difference. Internal environment disorder and improve the situation in group A than group B (P <0.05).4two groups of patients after treatment pain was significantly improved, there are significant differences for comparison with the baseline. At the same time the effect of treatment group (46.67%) than the control group (25.90%).ConclusionYang He Tang for treatment of ankylosing spondylitis (AS) than western medicine, improving spinal function and reduce the inflammatory response, immune response, also has a certain effect. Yang and Tang treatment of ankylosing spondylitis can also relieve pain, restore and to improve the function of the spine and peripheral joints, AS is more effective than western medicine group, and no significant side effects, is a safe and effective ankylosing spondylitis method of treatment.