The Clinical Research Of Treatment Of Moxibustion In Irritable Bowel Syndrome And The Influence Of The Quality Of Life

Purpose:To observe and objectively evaluate the clinical efficacy of treatments on patients with Irritable Bowel Disease (IBS) by Moxibustion with moxa stick plus Ginger-partitioned Moxibustion combination,and the change of Quality Of Life of before and after treatment, so as to study the influence on Quality Of Life of patients with IBS.Methods:A randomized controlled clinical trial is carried out.According to Rome Ⅲ diagnostic criteria,thirty patients with IBS who are brought into this study,are randomly divided into treatment groups(n=15,moxibustion with moxa stick,in Zhongwan point,both Tianshu points and Zusanli points,each time using a length of moxa stick per point,qod;plus Ginger-partitioned Moxibustion,in Shenque point,each time using5cones, qod,15times per course of treatment,observing on3courses) and control group (n=15, Pinaverium Bromide,50mg, po, tid, four weeks per course of treatment, observing on3courses).The change of main symptoms are observed and compared between the two groups.And the two tables of SF-36and IBS-QOL are used to evaluate patients’quality of life before and after the treatment. So that patients’ condition changes could be estimated.Results:All treatment of the30patients are completed. After12weeks treatment, there are statistical differences of the cure rate in terms of main sign and symptoms (p<0.05).The total effective rate treatment group is93.3%and control group is80%, the treatment group has a statistical difference to control group (p<0.05). The calculation of SF-36table shows that each dimension is improved in treatment group, so is the control group. The treatment group has a statistical difference (p<0.05), while the control group has no statistical difference (p>0.05) except RE and BP. The evaluations of treatment group in dimension RE and BP are both higher than control group (p<0.05). Scores in each dimension of IBS-QOL table have no statistical differences before treatment(p>0.05),with comparability. The calculation of IBS-QOL table shows that each dimension is improved in treatment group, so is the control group. The treatment group has a statistical difference (p<0.05), while the control group has no statistical difference (p>0.05) except FA and SX. Conclusion：(1)Two treatments described above are both effective, while Moxibustion with moxa stick plus Ginger-partitioned Moxibustion combination is more effective than Pinaverium Bromide.(2)The two tables of SF-36and IBS-QOL are appropriate for evaluating quality of life of patients with IBS.The two tables can be used to evaluate and compare the efficacy in terms of physiology,psychology and environment before and after treatment,so as to study the factors and cure mechanism of IBS.