Literature Research On Prescription Rule Of Oral Drugs For Osteoarthritis

Objective: To explore the application range and prescription rule of the oral drugs ofGuBi in Ancient and modern literature in the different periods, And further analyze itspathogenesis and its therapeutic treatment. For future clinical and scientific research toprovide document foundation and more explicit medication guide. Methods: Investigatemainly the oral drugs of osteoarthritis literature material of Traditional Chinese Medicnefrom the Qin and Han Dynasty to the modern times, and identify, reorganize the originaldocuments. There are441topical prescription in this study, Each other medicineinformation applications frequency analysis, variance analysis, cluster analysis, mathe-matical statistics method and combining analysis induction, formula metrology researchmethods, party card corresponding methods GuBi for use in formula of law of researchand analysis. Results: Cumulative frequency of Chinese herb reaches93.69%, which arefor restoratives Chinese Medicinal Herbs, Chinese Medicinal Herbs for invigorating theblood and removing blood stasis, Antirheumatic Chinese Medicinal Herbs, diaphoretics orexterior syndrome relieving Chinese Medicinal Herbs, warming the internal, ChineseMedicinal Herbs for promoting diuresis and resolving dampness, heat clearing ChineseMedicinal Herbs, Chinese Medicinal Herbs for calming the liver to stop endogenous wind,qi regulating drugs and antitussive and antiasthmatic Chinese Medicinal Herbs are themain treatment drugs for osteoarthritis. They are the main drug categories warm, neutraland cold and the most that accounted for88.77%in four nature. Sweet pungent and bitterare the most that accounted for93.40%in the five flavors. Cumulative frequency of liver,heart, kidney, spleen and lung is91.14%, Through the system clustering formed10clustering prescriptions. There are different in efficacy, four climates, the five kindflavors and pertaining meridian. Conclusion:1. The prescription rule of the oral drugs ofGuBi are as follows:(1) Used in conjunction treatment of Xinkai Kujiang and GanwenBingshi;(2) Adjusting viscera placidly to get rid of pathogens;(3) Fill in the diarrhea,diarrhea in complement,(4) insect drugs significant effect.(5) The vines of the genus, pass through into the network.2. General use in gansu and Michael essien, taste bitterprimarily, medicinal properties to warm, neutral, cold is given priority to, be in by the liver,kidney, the heart sutra by the lung, spleen, by primarily, focuses on the liver and kidneyspleen. Drug class to make up for restoratives Chinese Medicinal Herbs, ChineseMedicinal Herbs for invigorating the blood and removing blood stasis, AntirheumaticChinese Medicinal Herbs primarily.3. Through the prescription that the osteoarthritis ofbasic prescription type has five: Respectively for FengHanshiBi type, FengShiReBi type,TanShiNeiZu type, GanShenKuiXu type.4. Virtual, blood stasis, phlegm, Pathogenic isthe main factor of the disease, Total treatment on having to WenTong therapeutic mainly,and concurrently to remove stasis expectorant, dispelling rheumatic and tong collaterals.5.Through the analysisi of the10cluster prescriptions, special drug on the followingcategories: Rectifying the drug Chenpi Banxia, Qianghuo Duhuo, Duhuo Xixin,Rectifying and Centralizer drugs:Gouji Gusuibu, Chishao Baishao, Shengdi Mudanpi,Fuzi Ganjiang. Centralizer drugs:Huangqi Baizhu, Tusizi Gouqizi, Fuzi Rougui, DangguiShudi, Danggui Chuanxiong.