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The Correlation Of TCM Syndrome Of Primary Liver Carcinoma And The Change Of Liver Function Before And After TACE

Posted on:2013-01-14Degree:MasterType:Thesis
Country:ChinaCandidate:J ZhouFull Text:PDF
GTID:2234330374484778Subject:Chinese medical science
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Objective:Through testing the ALT,AST,ALB,TBIL and DBIL level of liver cancerpatients before and after TACE,we may explore the correlation between the changes ofliver function before and after TACE and TCM syndrome of primary1iver carcinoma,thenprovide the clinical basis for the study of integration of Traditional Medicine and WesternMedicine.Method:65patients,who were defined primary liver cancer for the firstdiagnosis and hade been done TACE treatment during be in hospital.Collecting thepatients’general information,including symptoms,signs,tongue,pulse and other clinicalinformations,then all the patients were divided into five clinical types of TCM syndrome:28cases of blood stasis type,10cases of spleen deficiency type,10cases of damp-heattype;9qi stagnation type,8yin deficiency type.Testing the ALT,AST,ALB, TBIL andDBIL level the day before TACE and on day3,day7and day14after TACE.We analyzethese data with the statistics software SPSSl9.0.Results:1. There were significantdifference between the level of ALT,AST,T-BIL and D-BIL on day3and on day7afterTACE and the level of ALT,AST, T-BIL and D-BIL the day before TACE(P<0.05).Therewere no significant difference between the level of ALT,AST,TBIL and DBIL on day14after TACE and the level of ALT,AST,TBIL and DBIL the day before TACE(P>0.05).The level of ALB has no significant difference(P>0.05).2. There weresignificantly different between five types of TCM syndrome distribution before and afterTACE (P<0.05).After TACE the cases of damp-heat type was gradually increased and thecases of spleen deficiency type was gradually decreased(P<0.05). But the cases of blood stasis type,qi stagnation type and yin deficiency type had less changed in single syndrome(P>0.05).3.The changes of liver function was obvious in damp-heat type patients(P<0.05). There were no significant difference between the remaining fourtypes(P>0.05).Conclusion:1.After TACE three days, primary liver cancer patients’ALT,AST, TBIL, DBIL increased rapidly,and after two weeks,they coule be recovered topreoperative level. ALB had no significant changes.2.Blood stasis type was more thanother types before TACE.The cases of damp-heat type was increased and the cases ofspleen deficiency type was decreased after TACE.3. The damp-heat type patients’liverfunction changed obviously.We Need to strengthen the nursing and treatment of thedamp-heat type patients before and after TACE.
Keywords/Search Tags:Liver cancer, TACE, Liver function, TCM syndrome
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