Effect Of Shenqi Lee Tang On Chronic Heart Failure Patients With Heart Function And Serum Bnp Effects

Objective:The chronic congestive heart failure (CHF) patients’blood brain natriuretic (BNP) concentration, heart failure score, TCM syndrome integral, heart function classification,6minutes’walk test distance indicators such as monitoring, observation of Shenqi Lixin granule in the treatment of CHF clinical curative effect and its mechanism of action.Method:60cases of CHF were randomly divided into treatment group and control group, the control group given by Western standards of heart failure treatment, the treatment group was treated with routine therapy was given based on Shenqi Lixin particle5g,3times daily with water. Observed before and after treatment in TCM syndrome integral, heart failure, heart function classification score, enzyme-linked immunosorbent assay for monitoring before and after treatment in two groups in the serum of the patients with BNP concentration changes, according to veraBittner reports a method for the observation group two patients6minutes’walk test distance, measurement of EF, E/A and other indexes of cardiac function in the treatment of the change before and after, observation of Shenqi Lixin granule in the treatment of CHF patients.Result:1.In two group patients after heart function classification, Lee’s failure to score, TCM syndrome integral, digoxin was stopped by are better than before treatment, the difference was statistically (P<0.01); group comparison showed the treatment group was significantly better than the control group (P <0.05)2.The two groups before and after treatment, patients of the6minute walk test distance and EF, E/A heart function indexes were improved obviously, the difference was statistically significant; while the comparison group results in treatment group was significantly better than the control group (P<0.05).3.the two groups before and after treatment, plasma BNP content have significant differences, in which the treatment group in the reduction of BNP was superior to the control group, the difference between two groups was significant (P<0.05).Conclusion:1. Shenqi Lixin granule can obviously improve the cardiac function of the patients with CHF index, shows that the method has good improve heart function.2. Shenqi Lixin granule can reduce body B type natriuretic peptide (BNP) content, the myocardial protective effects.3." Wen Yang Qi, activating blood circulation to remove water" as the basic method of Shenqi Lixin granule is effective in the treatment of CHF prescription.4. Combining traditional Chinese and Western medicine treatment. Compared with the pure western medicine treatment can better reduce the hypokalemia. reduce or even stop the diuretic or digitalis preparations, have better clinical safety and dependent.