172Cases Of Preterm Premature Rupture Of Membranes Were Analysed Retrospectively

Objective:To observe the risk factors of Preterm Premature Rupture Of Membranes (PPROM)and their effects on the pregnant women and infants。Method:The clinical data of172cases of preterm premature rupture of membranes,who are hospitalized in Division of Obstetric,the Qilu hosptial,Shandong University between January2008and December2011,are collected in order to analyse and compare the related factors and its influence on nothers and mewborns.We define the PPROM mothers and newborns as the object of observation(group A),the mother who don’t have special situation togather with these babys are difined as the control group (group B). According to the gestational age (GA),all cases are divided into two groups:GA28-34+0(group Al)and GA(34+1-36+6) group A2。Result:There are11503mothers delivery in our hosptial during that time and172of cases PPROM happene, accoutnting for1.50%of the hospitalization infants. There are57women in the Group A1. Among them,87.7%of them are the first time parturition.3of cases are multiple births(5.8%),the others are single births.There are60infants in this group,34boys and26girls, the7dead babys containe5boys and2girls. There are115women in the Group A2. Among them,85.2%of them are the first time parturition.7of cases are multiple births,the others are single births.There are122 infants in this group,69boys and53girls, The5dead babys containe4boys and1girls. There are350women in the Group B. Among them,90.8%of them are the first time parturition.14of cases are multiple births,the others are single births.There are364infants in this group,199boys and165girls, This group dead1boy.This study containes108women (62.8%)who are accompanying by abnormal circumstances and64women (37.2%) haven’t obvious factors.The four most common complications are the genital tract infection-. malposition、the breech presentation、multiple pregancy. Among the three group there are no obvious relation with the delivery pattern (P>0.05). The laten period between the membranes rupture to delivery have no significant effect on the delivery pattern (P>0.05).The new babys are have different results among the three group (P<0.05). In this study we also mark the infants Apgar score in the1st minute and the5st minute after birth,and then we analyze the Apgar score.As excepted,the three group have obvious relation about the Apgar score (P<0.05).In group A1,60infants’outcomes have different and obvious relation with the laten period between the membranes rupture to delivery,but has opposite result in the group A2. The most common complications about mothers was puerperal infection and postpartum hemorrhage. Among the three group there are obvious relation about the mothers puerperal infection (P<0.05) Among the three group there are obvious relation about the mothers postpartum hemorrhage (P>0.05). In group A,the mothers occur puerperal infection have different and obvious relation with the laten period between the Membranes Rupture to delivery,but has opposite result with postpartum hemorrhage. Using of the Dexmethasone, the newborns mortality no decreased (P>0.05), but the babys have Neonatal respiratore distress syndrome have obvious relation(P<0.05)。Conclusion:The PPROM has low incidence rate but if it is not mananged appropriately,it’s can lead to serious harm of maternal and newborn.The investigation suggests that the common high risk factors of PPROM including reproductive tract infection, breech presentation, gestational diabetes mellitus, multiple births and so on. With the increase ofthe gestasional age,the birth weight,the Apgar score,the newborns mortality decreased,but if the gestasional age exceed34weeks,we don’t suggest to use conservative treatment. Using of the Dexmethasone, the newborns mortality no decreased but the Neonatal respiratore distress syndrome cut down.