Preterm Premature Rupture Of Membranes-prone Factors And Outcome In Female Children

Preterm birth has been the perinatal morbidity and mortality, its incidence has tend to increased in recent years. The premature rupture of membranes is a major risk factor for preterm delivery. Premature rupture of membranes is the rupture of fetal membranes in labor before, for obstetric complications, The premature rupture of membranes means the occurrence of pregnancy within 28 to 37 weeks preterm premature rupture of membranes and ultimately to those. Preterm premature rupture of membranes so that the processing becomes difficult, and premature rupture of membranes of perinatal morbidity and mortality of children rather high, so appropriate to deal with premature rupture of membranes is to reduce child mortality perinatal key. Analysis of preterm premature rupture of membranes factors and mother-prone child outcomes for clinical work in prevention, treatment, PPROM sum up experience, reduce child mortality, perinatal, collected 42 cases of preterm premature rupture of membranes of the clinical data in our hospital during January 2007 to January 2,010 , analysis risk factors and the mother of their child outcomes combined with literature.Objective : Discussion the risk factors and the impact on maternal and child outcomes of preterm premature rupture of membranes (PPROM).Methods : Collected 42 cases of preterm premature rupture of membranes of the clinical data in our hospital during January 2007 to January 2,010, combined with the literature were analyzed retrospectively.Results : A total of 42 cases of preterm premature rupture of membranes, incidence of unknown causes in 14 cases(33.33%), 9 cases of breech presentation(21.43%), twin 7 cases(16.67%), flow history of≥2 times in 4 cases(9.52%), pelvic abnormalities, hypertension, each in 3 cases(7.14%), uterine malformations, each one cases of chronic cough(2.38%); natural childbirth in 14 case(s33.33%), hip traction in 2 case(s4.76%), 1 case forceps(2.38%), cesarean section 25 cases(59.52%); a total of 49 cases of newborns, Apgar score≤7 points in 6 patients(12.24%), body weight≤2000g 20 cases(40.82%), death or mental disabilities in 2 cases(4.08%).Conclusion : retrospective analysis 42 cases of preterm premature rupture of membranes in our hospital found that main factors for PPROM prone to abnormal fetal position (breech), and twin pregnancy mainly, followed by multiple intrauterine operating history and pelvic structural abnormalities. The treatment of preterm premature rupture of membranes should be based on different gestational age has taken various steps to improve the prognosis of female children. For gestational age <34 weeks, fetal lungs are not yet mature, anti-infective therapy should be based on the extended weeks of gestation, in order to promote lung maturation to gain time in order to reduce the incidence of neonatal RDS, mortality and the incidence of mental retardation later. In the extended gestation while monitoring the blood count and CRP, select the appropriate timing of termination of pregnancy, in order to achieve a good prognosis of the mother child health. For the fetal lungs have matured, upon inspection cervical conditions are ripe, can be observed, generally after the 24h self-labor rupture of membrane. The poor condition of the cervix who rupture of membrane after 24h, can be prostaglandin E2 (PGE2) or oxytocin induction of labor. A good prognosis of PPROM resulting from reasonable and timely termination of the treatment.