The Clinical Observation Of Shuangwenpishen Decoction In The Treatment Of Proteinuria Caused By Chronic Glomerulonephritis (Yang Deficiency Of Spleen And Kidney)

Purpose: To research through clinical trials to observe the clinical efficacy ofshuangwenpishen decoction to proteinuria caused by chronic glomerulonephritis (yangdeficiency of spleen and kidney), enrich traditional Chinese medicine theory and experienceof the treatment of chronic glomerulonephritis. To provid a basis for clinical use of drugs.Method: Selected from patients of proteinuria caused by chronic glomerulonephritis(yang deficiency of spleen and kidney) from The Department of Traditional Chinese Medicineat Jilin Province People’s Hospital since January2011to January2012. Selected qualifiedcases as subjects from them according to inclusion criteria, exclusion criteria,and randomlydivided the subjects to treatment group and control group (n=30). With basic treatment,special treatment of shuangwenpishen decoction to treatment group and nephritis Onyangcapsule to the control group, the two groups were treated for8weeks.Result: By statistical analysis, in terms of clinical efficacy, total effective rate was83.3%in the treatment group and was66.7%in control group. But between the two groups, thedifference had no meaning in statistics (P＞0.05). In terms of TCM Syndrome, the totaleffective rate was90.0%in the treatment group and was66.7%in control group. Between thetwo groups, the difference was statistically significant (P＜0.05). In aspect of reducingproteinuria, the treatment group was better than the control group (P＜0.05). No abnormalchange and adverse reactions was found that caused by the medicine during the treatment,which proved the safety of medicine.Conclusion: Shuangwenpishen decoction is efficacy to proteinuria caused by chronicglomerulonephritis (yang deficiency of spleen and kidney), which can improve the clinicalsymptoms and reduce proteinuria.