Research In Correlation Of Emotional Factors And Thyroid Diseases

Background:Thyroid diseases were belong to " ying " in TCM," Ying " was divided into " Qi-Ying "," Rou-Ying "," Shi-Ying "," Ying-Yong ", respectively equivalent to simple goiter, thyroid adenoma, thyroid cancer, thyroiditis in mordern medicine. Thyroid diseases were caused by poor emotional, diet disorder, inappropriate of climate and so on. Emotion was an important factor in the pathogenesis of thyroid diseases.Objective:This research uses Case-control to analysis the investigation result and to assess the role of emotional factors in the development of thyriod diseases from the perspective of traditional Chinese medicine.Methods:128patients with thyroid diseases and128patients without thyroid diseases participated in the retrospective study. All patients were diagnosed and treated in First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, of Endocrinology outpatient clinics from February2011to December2011. Thyroid diseases group and control group were followed in accordance with (1) age is similar (a difference of no more than3years old);(2) the same career (and for mental or physical);(3) a considerable level of education;(4) similar habits;(5) marital condition is same; Two groups of patients filled the same traditional Chinese medicine etiology information collection table, Life Events Scale (LES) and Trait Coping Style Questionnaire (TCSQ). To statistics and analysis the depression, thought, sadness and other emotional factors that caused by the negative life events the two groups of patients experienced in the nearly5years, the extent of the impact on patients and the coping style. The statistical processing used the SPSS17.0analysis software package to test the significance in measurement data with paired t-test, count data with chi-square test.Results:(1) There was no significant difference between the two groups in the basic information and prompted that there are comparability(P>0.05).(2)128patients with thyroid diseases experienced326different life events in the nearly5years, an average of2.89+1.19. While128patients experienced117different life events in the control group, an average of1.21±1.10. There are obvious differences between the two groups (P<0.05).(3)The results showed that the average score of life events units (LEU) of the thyroid diseases group was78.48±35.60points, while that of the control group was37.21±26.65points, the former was significantly higher than the latter (P<0.05)(4) The degree of LEU were ranked to no(0point), mild(1-50points), moderate(51-100points) and severe grade(more than101points).The results show that the intensity distribution of the negative life events are different between the two groups (P<0.05). The number of the thyroid diseases patients encountered moderate and severe life events is more than that of the control group obviously, while the number of the control group patients experienced no negative life events significantly is more than that of the thyroid diseases group.(5) In the content of the negative life events the results showed that the number of the negative life events in the marriage and family issues of the thyroid diseases group is clearly more than that of the control group (P<0.05).(6)About coping style, thyroid diseases group scored significantly higher than control group(P<0.05), deal with the negative life events in a positive way. there was no statistically significant difference in two groups (P>0.05).Conclusion:(1) The frequency of experienced negative life events the thyroid diseases group before being diagnosed at5years is higher than that of the control group obviously. It is that depression, thought, sadness and other emotional factors are related to the occurrence of thyroid diseases;(2) The degree of experienced negative life events in thyroid diseases group is greater in general; the negative life events mostly are moderate and severe;(3) The thyroid diseases group choose to use the negative coping style when they encountered the negative life events. The negative coping style is an unfavorable factor to thyroid diseases;(4) The negative life events which are a stressor cause functional disturbance of zang-fu if without deal with in time. Liver stagnation influence spleen function, spleen deficiency and, dampness retention qi stagnancy and blood stasis, therefore, qi stagnancy, dampness retention, blood stasis are important factors causing thyroid diseases. Kidney yang deficiency which also is another important pathogenesis cause five-zang yang deficiency and then arouse five-zang function imbalance.