Salivary Gland Basal Cell Adenoma:Reprot Of20Cases And Review Of The Literature

Objective:To evaluate the clinical and imaging features, pathologic characteristics, differential diagnoses, treatment and prognosis of Salivary gland basal cell adenoma.Methods:A total of twenty patients with salivary gland basal cell adenoma were treated in the second affiliated hospital of Zhejiang University from2009to2011, all of the cases with a more than half a year follow up. All cases were proved by operation and pathology. The clinical characteristics, imaging features, histological features, differential diagnoses, therapy methods and prognosis condition were analyzed. A review of all the similar cases published in the literature and comparison with the present series was performed.Results:SBCA predominantly influenced female patients above50years of age, and mainly occurred in the parotid gland. The swelling with well-defined margins was present for sever years and was slowly increasing in size without any pain. Tumors presented as well-encapsulated, round or oval masses on computed tomography (CT) and magnetic resonance (MR) imaging. MR features revealed low signal intensity on T1-weighted images, and high intensity on T2-weighted images together with the homogenous enhancement. CT features revealed marked contrast enhancement on the early phase, and there was a subsequent decrease in attenuation on the delayed phase. Needle aspiration cytology was characterized by uniform appearing basaloid cells associated with variable amounts of collagenous stroma. Pathological features showed uniform and regular basaloid cells mainly for the presence of trabecular, membranous, solid and tubular structures, without any chondromyxiod stroma appearance. SBCA were amenable to conservative resection such as local excision and superficial removal of the gland. The recurrence rate and malignant transformation of the SBCA was almost nonexistent except the membranous type.Conclusions:SBCA is a rare tumor which often suffering behind earlobes, with the similar clinical features of other salivary gland tumors. Surgery resection is the best therapy. Differential diagnosis must be established between pleomorphic adenoma, adenolymphoma, adenoid cystic carcinoma, acinic cell carcinoma and basal cell adenocarcinoma. Histology proven is the unique way to diagnose the SBCA, CT scan and needle aspiration cytology are also helpful.