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Gastrointestinal Stromal Tumors:Msct Manifestations And Risk Analysis

Posted on:2013-06-23Degree:MasterType:Thesis
Country:ChinaCandidate:R DongFull Text:PDF
GTID:2234330371977283Subject:Medical imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective through the gastrointestinal stromal tumor (GIST) of the CT imaging features and pathology, risk degree and two correlation, to the accumulation of clinical experience, improve the treatment rate.Materials and methods Retrospective analysis and collection at the same time, histopathological examination and immunohistochemistry in44cases of GIST CT data, By3the group image experts double blind method separate read, CT evaluation including:The tumor site, tumor size, morphology, fat clearance, calcification, density, growth pattern, aggrandizement, tumor or vascular, CT scan, arterial, venous phase and delayed CT value comparison; Grading of tumor by2002the United States National Institutes of Health (NIH) standard, classified as high risk group, medium risk group, low risk group and the low risk group, due to a very low risk group cases were less, for the convenience of the study, will be extremely low risk and low risk group merged into the low risk group. Using SPSS16.Osoftware package for statistical analysis, tumor, high risk and low risk of endangering the tumor site, tumor size, morphology, fat clearance, calcification, density, growth pattern, aggrandizement, peritumoral or intratumoral vessels between the statistical difference by using chi-square test, and CT scan, arterial, venous phase and the delay period between CT value difference with single factor analysis of variance, In order to tumor low risk, which endanger risk as the dependent variable (Y), there are differences in characteristics as independent variables on the risk of tumors are more variable step wise Logistic regression analysis.Result The tumor originated in the27cases of gastric wall,6cases of duodenum, jejunum and ileum in7cases,1cases of retroperitoneal colon,2cases,1cases of pathologically confirmed mesentery,5cases of very low risk, low risk in15cases, moderate in12cases,12cases of high risk, maximum tumor diameter19*13cm, the pathl*1cm, size was larger than5cm in29cases,5cml5cases,26cases of morphological rules,18cases of irregular shape, lobulated change,29cases of fat clearance clear,15cases with fatty fuzzy gap,10cases of visible calcifications,34cases without calcification in19cases,25cases of uniform density, uneven density, the necrosis liquefaction District, the tumor cavity shape growth in14cases,22cases with intraluminal growth, mixed growth in8cases,18cases of reinforcement uniform, uniform in26cases, no obvious enhancement of central necrosis,12cases of visible in or around tumor blood vessels,32cases showed no tumor or vascular. Using the chi-squared test analysis, tumor size, tumor morphology, fat clearance, calcification, density, growth pattern, aggrandizement, peritumoral or intratumoral vessels were associated with the risk of tumors have significant difference, the single factor variance analysis of tumor CT unenhanced, arterial phase, the venous phase and delayed CT and tumor risk no statistical difference, paired sample t test of the risk of arterial phase and portal venous phase between group CT value difference, tumor with progressive strengthening characteristics, multivariate stepwise Logistic regression analysis, only the mode of growth, morphological, and tumor vasculature to risk effect was statistically significant.Conclusion MSCT scan and dynamic enhanced scan may reflect the GIST pathology and blood supply features, GIST has some characteristics on CT manifestations, multi-slice spiral CT in gastrointestinal stromal tumor localization and qualitative judgement as well as the differential diagnosis of great value, multi-slice spiral CT decision risk, clinical on tumor grade, making treatment options provide important and valuable reference information.
Keywords/Search Tags:gastrointestinal stromal tumor, MSCT, risk
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