| Objective:(1) Explore the laryngeal cancer patients with perioperative nutritional status.(2) To study nutritional status of patients on the quality of life, and to compare the quality of life between nutritional risk and normal nutrition in patients.(3) To compare the incidence of complications, length of hospital stay and hospital costs between nutritional risk and normal nutrition laryngeal cancer patients.Methods:In this prospective cohort study, a consecutive series of76laryngeal cancer patients with ill for the first time in First Affiliated Hospital of Guangxi Medical University enrolled from April2011to December2011,72cases were male and4females, aged45to78years, the average age of59.47±8.70years. The establishment of a cohort study of patients with laryngeal cancer, conducted in two parts:The first part, Evaluation of all76patients included in the study of Nutritional Risk Screening2002to its nutritional status, and evaluation of quality of life of patients with medical outcome survey short scale-36entries (SF-36). Explore the impact of the nutritional status of patients with laryngeal cancer to its quality of life, and NRS2002for nutritional evaluation criteria, in accordance with the eight dimensions of the survey scale, well-nourished and malnourished patients quality of life. The second part of the study from the first part of the76cases of laryngeal cancer patients screened56patients met the inclusion criteria.53cases were male and3females, age45-76years, mean age58.95±8.48years. Record the patient’s clinical data, operative time of surgery, date, name of surgery, nutritional support conditions, complications, hospital costs. Analysis of good nutrition and malnutrition, the impact of patient-related clinical outcomes and hospital costs.Results:(1) This study found that48hours of admission, respectively, BMI and ALB evaluation in patients with laryngeal cancer, accounting for19.70%and26.3%of nutritional deficiencies.(2) Admission48h,nutrition risk screening:42cases of normal nutrition(55.3%);34cases of nutritional risk, accounting for44.7%.(3) Line laryngeal suspension resection surgery patients, screening by NRS2002, preoperative, postoperative nutritional risk tates were48.21%and85.71%.(4) Adimission48h body weight58.22+9.55kg, postoperative7d body weight51.32±8.38kg, a drop of6.90±1.72kg, P<0.05, the difference was statistically significant.(t=30.070, P=0.000).(5) Admission48h laryngeal cancer patients quality of life survey results show that normal nutrition group and nutritional risk group in physiological functions (PF), bodily pain (BP), energy (VT), social functioning (SF) and role emotional(RE)dimension difference was statistically significant, P<0.05(P=0.004,0.029,0.026,0.005,0.047), nutritional risk group scored lower than well-nourished group; normal nutrition group with nutritional risk group in the physiological function (PF)three dimensions of overall health (GH) and mental health (MH) was no significant difference, P>0.05(P=0.433,0.674,0.172).6. Nutritional support for utilization of the nutritional risk group is higher than normal nutrition group, admission48h normal nutrition group nutrition support utilization rate of41.38%, and nutritional risk group nutritional support for the utilization rate of81.48%; postoperative7d normal nutrition group nutrition support utilization rate of12.5%, nutrition risk group nutritional support utilization rate of68.75%.(P<0.05).(6) Admission48h and postoperative complications of the7d Nutrition normal group the incidence of6.90%and12.5%, nutritional risk group the incidence of complications was22.22%and14.58%, respectively;48h of admission and admission7d of nutritional risk group hospital stay were27.41±12.59and29.75±14.32days, and normal nutrition group, the total duration of hospitalization was26.33±13.02and26.42±12.51days, respectively. Admission48h and the admission7d nutritional risk group postoperative hospital stay was20.41±10.70and24.13±14.69days, and normal nutrition group of postoperative hospital stay was19.93±12.86and19.52±11.16days, respectively. Admission48h and admission7d nutritional risk group hospitalization costs were27936.49±18161.36and29783.32±21284.32, normal nutrition group hospitalization cost was26433.23±16574.53and26783.10±16743.81. Was no significant difference (P>0.05).Conclusions:(1) Nutritional risk was present in44.7%and postoperative the7d nutritional risk incidence is significantly increased.(2) Nutritional risk the quality of life in laryngeal cancer patients with worse than normal nutrition.(3) In this study, nutritional risk have not yet found the incidence of larynx cancer patients with postoperative complications, length of stay and hospital costs have an impact. |
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