| ObjectiveTo Observe the clinical curative effect on treatment of chronic functional constipation of qi asthenia by buzhong yiqi tang.MethodsThe Prospective RCT research method was adopted in the present study and a total of78patients with chronic functional constipation of qi asthenia which were randomized into2groups. The control group (n=38) was treated with Lactulose Oral. Therapeutic group (n=40) was treated by buzhong yiqi tang. Period of treatment was3months. Constipation symptoms score and other concomitant symptoms score were evaluated before and after treatment of the2groups. The actual number of patients whose defecation frequency per week was up to1or2days per time, the score of constipation symptoms, the score of other concomitant symptoms, and the integrative score of symptoms after the treatment were recorded and evaluated. The2groups pretherapy and post-treatment consequence were compared between interclass and intragroup separately, the results were analyzed and treated using statistical methods.ResultsMain outcome index (Defecate frequency):The actual number of patients whose defecation frequency per week was up to1or2days per time after3months:control group (n=26), therapeutic group (n=32);The2groups were not statistically significant difference (P>0.05). The secondary outcome index (rating scale):①Score of constipation symptoms:therapeutic group rating reduce (9.95±2.23)(P<0.05), control group reduce (9.95±2.23)(P<0.05). Comparison among groups (P>0.05), the2groups were not statistically significant difference. Total effective rate (ORR):therapeutic group was95.0%, control group was94.7%, the2groups were not statistically significant difference in improving constipation symptoms (P>0.05).②Score of other concomitant symptoms:therapeutic group rating reduce (22.84±4.91)(P<0.05), control group reduce (7.68±6.28)(P<0.05). Comparison among groups (P<0.05), the2groups were statistically significant difference. Total effective rate (ORR):therapeutic group was100.0%but control group was42.1%, therapeutic group was better than control in improving other concomitant symptoms of constipation symptoms (P<0.05). Evaluation of comprehensive curative effect Total effective rate (ORR) of therapeutic group was100.0%, Total effective rate (ORR) of control group was68.4%, the2groups were statistically significant difference (P>0.05), therapeutic group was better than control in improving total therapeutic effect.ConclusionIt was definite superior effect that treatment of chronic functional constipation of qi asthenia by buzhong yiqi tang. It could rival Lactulose that Buzhong yiqi tang improved constipation symptoms, and it had better effects on the other concomitant symptoms with constipation and clinical comprehensive effect than Lactulose. |
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