Study On The Relationship Between Microalbuminuria And Carotid Intiama Media Thickness In Type2Diabetes Meliitus

Objective: To investigate the relationship between microalbuminuriaand carotid intima media thickness in type2diabetes mellitus.Methods: One hundred and twenty nine patients with type2diabetesmellitus,were divided into two groups according to the24hours’microalbuminuria.The seventy-five patients in normal albumininuria group had24hours’ microalbuminuria <30mg/dl and the fifty-four patients inmicroalbuminuria group had24hours’ microalbuminuria30mg/dl~300mg/dl.And the patients in microalbuminuria group were divided into three groupsaccording to the level of microalbuminuria. Underwent neck vascular colorDoppler ultrasonography to evaluate carotid intiama media thickness and thepresence of coronary atherosclerotic plaque,The carotid intima mediathickness(CIMT), age, body mass Index(BMI),blood pressure, the history ofhigh blood pressure, blood glucose, glycosulated hemoglobin, blood lipid,history and the presence of coronary atherosclerotic plaque were comparedbetween groups.Results: There was significant difference between groups about theCIMT(P<0.05). There was significant difference between groups of thepercentage of the patients who had coronary atherosclerotic plaque (P<0.05).There was also significant difference between the two groups of FBG,PBG,glycosulated hemoglobin, TC, history, blood pressure, and the history of highblood pressure (P<0.05). There was no significant difference between groupsof age,BMI, TG, HDL, LDL (P>0.05). Spearman correlation coefficientrevealed that there was significant correlation between microalbuminuria andcarotid intima media thickness in type2diabetes mellitus.Conclusion: There was significant correlation between microalbum -inuria and carotid intima media thickness in type2diabetes mellitus.