Diabetes Microvascular Disease Screening And Related Factors Analysis

With the impact of people’s habits change and improvement in the level ofaging and other factors, the incidence of diabetes is increasing year by year, thelatest statistics from the global incidence of diabetes the number of shocking.Adults over the age of20of China’s diabetes prevalence rate of10%, type2diabetes accounted for90-95%of major chronic microvascular disease is diabeticnephropathy and retinopathy, and ultimately can lead to end-stage renal diseaseand adult acquired blindness. Complex mechanisms of microvascularcomplications of T2DM, the specific reasons not yet entirely clear, on the basis ofhigh blood sugar for a common cause of can produce characteristic changes.Diabetic nephropathy is the main cause of death in type1diabetes, in type2diabetes, the cause of death after cardiovascular and other macrovascular disease.Reveals the link between the two diabetic microangiopathy and differences,especially in larger patients with longer duration and age, to better predictdiabetes disease of great clinical significance. Urine microalbumin (MAU)appear increased glomerular permeability of the body, suggesting that earlykidney damage, the possible metabolic abnormalities caused by high blood sugar,not only assessment of microvascular disease, and even predict cardiovascularand other vascular events. Diabetes prevention and treatment guidelinesemphasize again that all patients with T2DM Diagnosis was confirmed by routine screening for MAU in positive and effective treatment does not appear before thepersistent microalbuminuria, some patients can be reversed in2010. As personalvisible blood vessels, retinal microvascular provide an intuitive basis for theunderstanding of systemic microvascular disease. In April2002, joint meeting ofU.S. and international ophthalmology unified diabetic retinopathy classification,the universal application of the single-vision-free mydriatic digital fundusphotography screening apparent diabetic retinopathy clinic. Diabetic retinopathymay increase due to hemodynamic changes and blood viscosity, capillary microthrombosis, caused by hypoperfusion of early retinal ischemia and hypoxia,vascular dysfunction, increased permeability of the ingredients spill, after thedevelopment of micro cycle heavy degree of disorder and angiogenesis seriouslyaffect vision. Chronic complications of diabetes is mostly irreversible change isparticularly important to delay the clinical progression of prevention and control,diabetic nephropathy and diabetic retinopathy as a simple means of detection dueto its pathogenesis, there is a corresponding homogeneity, both test resultsassessthe complications of diabetes, showing the tip of the iceberg of the chroniccomplications, and strive to take preventive measures, early to predict, andintervention to reduce cardiovascular and cerebrovascular diseases and reduce therisk of death, to provide early warning for patients in clinical work, to betterimprove diabetes health education.In this study, randomly selected from March2010to November2011fortreatment in our hospital diagnosed as type2diabetes368cases,180cases of men,188cases of women aged20-80years old, average51.3±2.3years,because patientsthe prevalence and incidence of complications was no significantgender differences, respectively, divided into two groups based on age andduration of study, the grouping method based on age <40years of age,40to60age group>60years of age threegroup of patients, Second study packet durationof28years from the onset, can be divided into disease duration <1year,1year to15years, more than15years, three groups of patients, detection of urinaryalbumin and retinopathywere controlled. Evaluated and diagnosed the disease asmay error cases far as possible into the group. Patient specimens from24hoursurine and note the amount of urine after submission of urine albumin in the mixquantitative, or determination of urinary albumin/creatinine instant urinespecimens; Diabetic retinopathy to check patients in the darkroom to the CanonNon-Mydriatic Retinal Camera platform underwent the monocular check, likepaper, printing in color analysis. In this paper data to use spss11.01statisticalsoftware for data processing. The measurement data x±s and data werecompared with single factor analysis of variance, t test, chi-square test, P <0.05was considered statistically significant, P>0.05was not statistically significantamong the groups.Of this study are as follows (1) type2diabetes DN prevalence was28.3%(104/368), in which the early nephropathy of16%(59/368), clinical nephropathy7%(27/368) in the course of DN patients is significantlyhigher than that ofnon-nephropathy (P <0.05), duration, clinical kidney disease duration longer than patients with early diabetic nephropathy (P <0.05), duration, DN patients and agewas not significantly related (P>0.05), no significant statistical difference.(2)type2diabetes DR prevalence of17.5(58/368), in which nonvalueaddedretinopathy (BDR)9%(31/368), value-added retinopathy (PDR)7.3%(27/368),DR course and age of the patients was significantly higher than the NDR patients(P <0.05); of PDR in patients with disease duration and age were significantlylonger than the BDR (P <0.05).In summary, diabetic nephropathy and diabetic retinopathy is a major chronicmicrovascular disease in patients with type2diabetes, its early diagnosis,effective treatment and prognostic evaluation in clinical work is very important,this study by the detection of urine microalbumin screening and diagnosis ofdiabetic nephropathy, a singleFree vision mydriatic digital fundus photographyscreening for diabetic retinopathy, the prognosis of patients with both test resultsto assess the complications of diabetes, to provide the appropriate clinicalguidance, control the development of clinical end-stage renal disease andblindness do a good job warning. Combination of domestic and foreign expertsand scholars from many perspectives, The findings were as follows:(1) urinaryalbumin determination and non-mydriatic camera examination of the fundus canbe used as screening and diagnosis of diabetic nephropathy and retinopathy,convenient and easy to diabetic microvascular diseasethe condition assessment ismeaningful and should be widely used in clinical work.(2) type2diabeticretinopathy prevalence with the growth of disease duration and age increased, condition aggravated with the disease and age.(3) type2diabetic nephropathyprevalence and the severity increased with the duration of growth, littlecorrelation and age.(4) in patients with diabetic retinopathy have kidney disease,long-term clinical nephropathy may be associated with retinopathy, there isdiabetic nephropathy, retinopathy assessment of kidney disease condition forretinopathy warning.