Analysis Of Etiology、 Risk Factors And Prognosis In Young Adults Cerebral Hemorrhage

Objective: To explore the etiology,risk factors, clinical manifestations and prognosisof young people cerebral hemorrhage,for clinical high-risk groups to provide a basis forpreventing risk factors.Methods: Collect and select955young adults patients with cerebral hemorrhage indepartment of neurology and neurosurgery in Jilin university Bethune first hospital duringJanuary2001to June2011. Their basie clinical data were analyzed retrospectively, usingSPSS18.0statistical software of statistical analysis, The age of onset, trends, univariateanalysis using the X~2test. Cause of the bleeding site Prognosis rank sum test. Observeetiology, risk factors and prognostic features of these paitents.Results:1Epidemiology: young ICH accounted for11.28%of the same period the totalcerebral hemorrhage, which accounted for68.27%of men and31.73%for women; themean age is37.22±7.01years; divided in accordance with the onset of the season, springincidence of316cases (33.1%), summer disease189cases (19.8%), the fall of incidence of148cases (15.5%), winter incidence of302(31.6%), the high incidence of young ICH is inwinter and spring.2Cause of young ICH: a clear cause in756cases (79.16%), including hypertension587cases (61.47%), vascular malformations in65cases (6.81%),21cases of the bloodsystem diseases, while22cases of tumor apoplexy, Cavernous hemangioma in12cases,14cases of pregnancy or in the puerperium,18cases of moyamoya disease.199cases(20.84%) can’t find the cause, and17cases of other reasons.3Risk factors: during the574cases in the department of Neurology, the risk factors is:hypertension313cases (54.53%),with smoking were136(23.70%) and with alcoholconsumption were182(31.71%).previous history of stroke were32cases(5.57%), familyhistory of cerebrovascular disease in166cases (28.92%),hypercholesterolemia in103cases(17.92%), high low-density lipoprotein hyperlipidemia in162cases (28.22%).4Bleeding sites: the locations of ICH were mainly at putaminal hemorrhage, cantionsabout432cases,258cases lobes of the brain hemorrhage,136cases of thalamic hemorrhage cerebellar hemorrhage in49,26cases of stem hemorrhage, intraventricularhemorrhage in22, the caudate nucleus bleeding in10, the corpus callosum hemorrhage in2, and two cases bleeding in parasellar.5Prognosis of youth ICH: recovery in61cases (6.39%), improved in652cases(68.27%), healed142cases (14.87%),101cases of death, the fatality rate was10.58%, thecause of death as follows: herniation and central respiratory and circulatory failure in72cases,14cases of sudden cardiac arrest, concurrent DIC5cases with pulmonary infectioncaused by respiratory failure, three cases of serious electrolyte disorder with MODS (n=5),two cases of central diabetes insipidus.Conclusions:1In recent years，the proportion of youth cerebral hemorrhage in cerebral hemorrhageis increased year by year and chiefly in male patients. More disease is depend in winter andspring.2The etiology of Youth cerebral hemorrhage is diversity, the main reasonis hypertension and the second is Vascular malformation. There are still a large number ofCryptogenic ICH. and the hemorrhage mainly located in lobes.3Risk factors: a history of hypertension, smoking, alcohol consumption, familyhistory of stroke, hyperlipemia may be associated with youth ICH.4The in-hospital fatality rate of young adult ICH was10.58%. blood diseases andmultiple focal cerebral hemorrhage lead to higher mortality of young ICH. The major causeof death was brain heria and respiratory or circulatory cpllapse.5Most of the young patients with cerebral hemorrhage have favorable prognosis. Weshould not only prevent the recurrence of ICH, but also to intervent the risk factors ofhigh-risk populations.