PYM And Dexamethasone Combined With Isotope Treatment Of Pediatric Maxillofacial Mixed Hemangioma Clinical Analysis

Objective: Hemangioma is a most common pediatric soft tissue benign tumors, the majoritywithin a few weeks after birth , occurs in the skin, mucous membranes . Mixed hemangiomagrowth in the maxillofacial region , with a lot of aggressive , seriously affecting the facialfunction and appearance . Clinical treatment is mainly surgical excision, sclerotherapy , hormoneinjections , Pingyangmycin intralesional injection therapy , isotope application therapy and lasertherapy . With the development of society, aesthetic requirements , the current treatment has beendifficult to meet the needs of patients . In this study, PYM and dexamethasone intratumoralinjection therapy and isotope ⁹⁰Sr applicator treatment together on a mixed hemangioma of themaxillofacial treatment，to observe the efficacy and adverse reactions , to seek an effectivemethod of treatment of pediatric maxillofacial mixed hemangioma .Methods: Select 18 cases to the pediatric clinic of our hospital from December 2009 toDecember 2011 , the maxillofacial region in children with mixed hemangioma . Male 8 cases ,10 female , male to female ratio of 1:1.25 . Mean age : 15 cases under the age of 1- 3 - year - old ,3 - to 6 - year - old one cases . Surface capillary hemangioma part erythema mole of 11 cases ,seven cases of strawberry hemangioma . Intratumoral injection of PYM and ⁹⁰Sr applicatorcombination therapy . Observe the clinical effects and adverse reactions and efficacy follow-upassessment .Results: PYM in combination with dexamethasone intratumoral injection , the injection varyingdegrees of swelling and pain. Tumor of generally 10-15 days after injection soft and tough, andreduce the size of the hemangioma . By isotope ⁹⁰Sr applicator treatment about a week after thesurface of cortical capillary aneurysm desquamation . Desquamation is complete tumor colorlighter . The clinical efficacy : 18 patients were cured 12 cases （ 66.7% ） , the basic cure in 5cases （ 27.8% ） , effective 1 cases （ 5.5% ） , and 0 cases （ 0% ） , total effective rate was 100% .The most common adverse reactions were fever , 4 cases of children with intratumoral injectionof Pingyangmycin fever after dexamethasone treatment , the body temperature up to 37.8°Cwithin 48 hours of symptoms . Other adverse reactions include one cases of tumor surfaceblisters rupture, 2 cases of pigmentation , and one cases of intratumoral injection of a rash .Conclusion: PYM and dexamethasone intratumoral injection with isotope ⁹⁰Sr applicator jointtreatment of pediatric maxillofacial mixed hemangioma is simple , safe and effective , it does notchange the the maxillofacial normal anatomy and function . Pingyangmycin intralesional injection in the treatment of cavernous hemangioma of deep isotope application therapy to solvethe problem of surface capillary hemangioma . Dexamethasone in addition to the hemangiomatreatment also reduces the adverse reactions caused by PYM injections . PYM anddexamethasone intratumoral injection of precise isotope ⁹⁰Sr applicator combination therapypediatric maxillofacial mixed hemangioma efficacy in clinical practice.