Carotid Atherosclerotic Plaque And Cerebral Infarction And Related Risk Factors

Objective1. To investigate the relationship between carotid atherosclerosis plaque and ischemic cerebrovascular disease.2. To explore the relationship between serum superoxide sensitivity C-reactive protein (hs-CRP), homocysteine (Hcy), uric acid (UA) levels and carotid atherosclerotic plaque and character of plaque.MethodSelect subjects from Gongyi People Hospital from June2010to June2011aged45-75years old.200subjects were healthy,500patients with ischemic cerebrovascular disease hospitalization routine color Doppler ultrasound examination. The shape and nature of atherosclerotic plaque between two groups were compared. The incidence of atherosclerotic plaque were also calculated.Choose150cases from500cases conventional measuring high sensitivity C-reactive protein, homocysteine, uric acid and analysis of differences in the serum of hs-CRP, Hey, and the UA level.Results1. The incidence of carotid atherosclerotic plaque of normal people was38%,and65%of ischemic cerebrovascular disease patients, the difference was statistically significant. Ischemic cerebrovascular disease group were mainly soft plaque,while the control group were hard plaque.2. hs-CRP, Hey, and UA levels under the no-patch group, the stable plaque group and unstable plaque group increased successively.Conclusion1. The ischemic cerebrovascular disease has high incidence of carotid atherosclerotic plaque.The incidence of unstable plaque in patients with carotid atherosclerotic plaque was significantly higher than that of stable plaque group.2. hs-CRP, Hey, and UA may be risk factors of plaque stability or otherwise of.