The Correlations Between Central Corneal Thickness And Non-contact Intraocular Pressure Of Children With Ocular Hypertension

Objective Explore the relationship and clinical significance of centralcorneal thickness(CCT) and ocular hypertension(OHT)children’s noncontactintraocular pressure(NCIP).Methods22cases of non-contact tonometer(NCT) to check intraocularpressure(IOP) children in our hospital from July2009to July2010,43eyes (age4-14years old) as the OHT children group, the Orbscan Topography II anterior segmentanalysis system to measure CCT and the establishment of OHT adult group11cases,20eyes and normal IOP in the control group33cases,66eyes; All of them werefollowed up for3-6months. the relationship between its Gender, Eye, Diopter, CCTand IOP were analyzed.Result1.All of the subjects average CCT of575±42um; The CCT ofOHT children group(607±30um), and OHT adult group (593±23um) are thickerthan the control group with normal IOP (548±34um), there are statisticallysignificant differences (P≤0.000). and there is no significant difference between CCTof OHT children group and OHT adult group.2.OHT children group22cases,43eyes, age range from4to14year, the averageage is9.82years old; IOP range22-40.5mmHg, average26.60±3.30mmHg;10males and12females, there is no significance between IOP and Gender(P=0.09>0.05);22Right eyes,21Left eyes, there is also not statistically significant in thedifference of IOP(p=0.084>0.05); Diopter range as follows:(+6.75~-9.00)D, theaverage diopter:(-0.67±2.88) D, which hyperopia in12eyes, low myopia <-3.00D (including emmetropia) in22eyes, and moderate myopia-(3.00~6.00) D in8eyes,but high myopia(>6.00D)only1eye; IOP was no statistical difference in the differentrefractive status. CCT is in the range of (531-674) um, average (607±30)um, CCTand sex, eye diopter differences were not statistically significant.3.CCT and NCIP in the normal group was positively correlated (Pearson r=.502; P=0.000), the linear regression equation for: Y=-4.897+0.037X (F=21.509, P=000).That is, the CCT per additional100um, NCIP can rise3.7mmHg. And CCT in theOHT adult group was positively correlated with NICP (Pearson r=0.447; P=0.024).Linear regression equation for: Y=4.523+0.049X (F=4.504, P=0.048). CCT andNCIP in OHT children group was no significant correlation.Conclusion1. The CCT of OHT children and OHT adult was obviouslythicker than the normal, while the difference of CCT between OHT children and OHTadult was no significant.2.The CCT and NICP and Gender.Eye.Diopter(spherical) were no significantcorrelation.3. The CCT and NICP in normal and OHTadult were positively correlated whilethey did not significantly associated in OHT children.4. In clinic OHT children should be routinely performed CCT in check, and thecharacteristics of OHT children is different from the adult;Whether CCT can befeasibile as a predictor of glaucoma progression needs further research, it should becombined with the OCT, Visual Field and other tests as a comprehensive analysis ofOcular Hypertension. close clinical follow-up should be adopt to avoid misdiagnosisand missed diagnosis.