Font Size: a A A

Buqihuoxue Set Halo Party Treatment Of Posterior Circulation Ischemic Vertigo Clinical Research

Posted on:2012-06-01Degree:MasterType:Thesis
Country:ChinaCandidate:T K LiFull Text:PDF
GTID:2234330362463767Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
ObjectiveBe observed halo side Buqihuoxue type of Qi and Blood circulation ischemic vertigoafter the clinical efficacy and safety, and explore its mechanism for clinical application.Methods1.Clinical data: All cases100cases2010-06to2011-04Department of Neurology,Affiliated Hospital of Hebei University of Integrative Medicine clinics and patients.Randomized, parallel methods, the ratio of1:1, divided into control and treatment group,50patients. All cases are in line with Shi Yuquan "Practical Neurology ’1994edition of thediagnostic criteria; At the same time meet the standards of TCM (qi deficiency blood stasis).2Sex, age, disease duration, clinical manifestations and basic balance MBI score, the statisticaltest, the difference was not statistically significant (p>0.05), comparable.2.Drug Usage: All patients were given routine control of various disease risk factors,such as Hypertension, high cholesterol and high blood sugar. Control group was giventwo-dimensional thirty-seven Cinnarizine Capsules1Grain, bid Oral;5%glucose250ml+Shuxuening injection20ml Intravenous infusion,qd,15~30drop/min,14d per course oftreatment. Treatment group were treated based on the additional services set halo partyBuqihuoxue: Astragalus, ginseng, angelica, peach kernel, safflower, Chuanxiong, red peony,Tianma, earthworm, Achyranthes, dry summer and head, chrysanthemum, licorice, one drugper day, Decoction twice filtrate400ml,once200ml, Fasting morning and evening hoursservice,14d per Treatment. End of treatment, the statistical effect.3.Efficacy and Safety Testing: The two groups of patients before treatment and aftertreatment for daily living score, the clinical therapeutic efficacy, by contrast TCD observedbefore and after treatment of bilateral vertebral arteries and basilar artery hemodynamicparameters change; testing coagulation, observed and recorded by the efficacy evaluationstatistics. Simultaneous detection of blood, urine, stool; liver and kidney function; as a safetytest statistics. 4.Statistical Methods: Count data(χ~2)test, Measurement data with the t test, Level datawith Ridit test.Result:1.Determine the clinical efficacy analysis: Recorded before treatment(that day)、2d、3d、5d、7d、14d、the onset of vertigo.According to "Chinese medicine clinical researchguidelines" to determine the clinical efficacy. Two clinical total effective rate p <0.05,significant difference. Control group before and after treatment of vertebral-basilar arteryVm, Vs change compared p <0.05, significant difference. Between the two groups aftertreatment, vertebral-basilar artery Vm, Vs change compared p <0.05, significant difference.Two groups of patients before and after treatment of daily living scores p <0.05, significantdifference; after treatment between the two groups of daily living scores p <0.05, significantdifference. Two groups of patients before and after coagulation compare p <0.05, significantdifference; between the two groups after treatment compared coagulationp <0.05, significantdifference.2.Adverse reactions and side effects: Treatment and control groups in clinical drugtreatment, no obvious adverse reactions and toxic side effects. Three conventional, liver andkidney function tests, were not there before and after treatment and treatment-relatedabnormalities. Halo party that Buqihuoxue be non-toxic, no side effects.ConclusionThe results show that: Comparison of clinical efficacy p<0.05, significant difference.Treatment group before and after vertebral-basilar artery Vm, Vs change compared p <0.05,significant difference. Between the two groups after treatment, vertebral-basilar artery Vm,Vs change compared p<0.05, significant difference. Two groups of patients before and aftertreatment of daily living scores p<0.05, significant difference; after treatment between the twogroups of daily living scores p<0.05, significant difference. Two groups of patients before andafter coagulation compare p <0.05, significant difference; between the two groups aftertreatment compared coagulation p<0.05, significant difference. Given that Buqihuoxue halo decoction vertigo treatment of posterior circulation ischemia (blood stasis type) of a clearclinical efficacy. While by the drug safety testing also showed that the drug safe, reliable,non-toxic, no side effects, have better prospects for clinical application.
Keywords/Search Tags:Posterior Circulation Ischemia, Vertigo, Qi and Blood Stasis, Buqihuoxue Set Halo Party
PDF Full Text Request
Related items