| Objective: The related factors of poststroke sleep disturbances werestudied in order to provided the rationale for the diagnosis, prophylaxis andtreatment.Methods: The61patients who suffered from stroke were studied in theFourth Affiliated Hospital of Hebei Medical University from September2011to January2012. The standard of diagnosis was accorded with the reviseddiagnostic criteria of the Chinese society of the fourth session of nationalcerebrovascular disease academic meeting in1995. The patients aged from41to83, mean age61.86±11.81years,39males and22females. No sleepdisorder before premorbid period. Eliminating gloomy, anxious and psychoticpatients. All had to refer to the diagnostic criteria of clinical sleep disorderstudy within a week. Over-slept diagnoses were based on patients' medicalhistory, principle actions (including housholds' descriptions), and dailysleeping hours＞12, bedtime＜5mins. Athens insomnia scale (AIS) was usedto evaluate the insomniacs, sleep disorder was defined as AIS scores whatwere more than6. All patients were divided into two groups in line with thestandard of diagnosis:①There were26cases in sleep disorder group, aged43～83years, mean age63.65±12.61years,17males and9females.②Therewere35cases in control group, aged41～81years, mean age60.54±11.19years,22males and13females. Comparatively analyzed the clinical data(including gender, age, anamnesis, apoplectic part, apoplectic type and thedamage degree of nervous functions). Applying SPSS13.0software to make astatistic dispose to the data, and the counting numbers should be signified bypercentage, applying chi-square test or fisher's exact test to make the checkout,P＜0.05showed there was statistic difference.Results:1Common data: Compared the two groups for the gender, age,anamnesis, apoplectic part, apoplectic type and the damage degree of nervous functions respectively, we could see that there were26cases in sleep disordergroup,17males (65.38%) and9females (34.62%), the ratio of males tofemales was1.9:1. The minimal age of the patients was43years, the maximalage of the patients was83years, mean age63.65±12.61years. There were35cases in control group,22males (62.86%) and13females (37.14%), the ratioof males to females was1.7:1. The minimal age of the patients was41years,the maximal age of the patients was81years, mean age60.54±11.19years.Comparing the gender and mean age in sleep disorder group with the controlgroup, it showed no statistic differences (P＞0.05). But in the different agegroup: There were4cases (36.36%) in group of the patients whose age lessthan50years, there were6cases (40.00%) in group of the patients whose agebetween50～60years, there were8cases (42.10%) in group of the patientswhose age between61～70years, there were8cases (50.00%) in group of thepatients whose age greater than70years, there was statistic differences (P＜0.05). In the sleep disorder group there were17cases with hypertension(56.67%),11cases with diabetes mellitus (64.71%), and14cases withcoronary heart disease (60.87%). In the control group there were13cases withhypertension (43.33%),6cases with diabetes mellitus (35.29%), and9caseswith coronary heart disease (39.13%). Comparison of the past medical history(hypertension, diabetes mellitus, coronary heart disease) between the sleepdisorder group and control group, there was statistic differences (P＜0.05).2Clinical features2.1The incidence and clinical features of sleep disorder:There were26cases (42.62%) who suffered from sleep disorder in all patients,8cases with hypersomnia (30.77%),4cases with woke up early in themorning (15.38%),5cases with frequent awakening (19.23%),4cases withsleep difficulties (15.38%),4cases with stay up all night (15.38%), and1caseassociated with mental symptoms (3.86%). There were7patients who sufferedfrom sleep disorder among the10cases who suffered from hemorrhagic stroke,5cases with hypersomnia (50.00%), and2cases with insomnia (20.00%).There were19patients who suffered from sleep disorder among the51caseswho suffered from ischemic stroke,3cases with hypersomnia (5.88%),16 cases with insomnia (31.37%). There were7cases (70.00%) who sufferedfrom sleep disorder in the hemorrhagic stroke group, and there were19cases(37.25%) who suffered from sleep disorder in the ischemic stroke group, thetwo groups had statistic differences (P＜0.05). There were5cases withhypersomnia (50.00%) in the hemorrhagic stroke group, and there were3cases (15.78%) with hypersomnia in the ischemic stroke group, the two groupshad statistic differences (P＜0.05).2.2The location of stroke: There were7cases (26.92%) who suffered from sleep disorder in the left-hemisphere strokegroup, and there were11cases (52.83%) who suffered from sleep disorder inthe right-hemisphere stroke group, there was no statistic differences (P＞0.05).The incidence of sleep disorder for the thalamus stroke, the basal gangliastroke, the frontal stroke, the cerebellum stroke, the brainsterm stroke were50.00%,45.45%,33.33%,50.00%,44.44%, but because there were notenough patients, it could not analyzed that sleep disorder was related to thelocation of stroke.2.3The type of stroke: There were7patients (70.00%) whosuffered from sleep disorder in hemorrhagic stroke group, and there were19patients (37.25%) who suffered from sleep disorder in ischemic stroke group,the two groups had statistic differences (P＜0.05).2.4Nerve function damagedegree: The26patients who suffered from sleep disorder all had differentnerve function damage degree, in accordance with the NIHSS,19cases withslightly nerve function damage (36.54%),7cases with moderate to severenerve function damage (77.78%), the two groups had statistic differences (P＜0.05).Conclusion: Sleep disorder after stroke was rather common, it was notrelated to the gender and apoplectic part, but it was connected with the age,anamnesis, apoplectic type and the damage degree of nervous functions. |
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