| Objective:Through the follow-up investigations by SARS patients of the Beijing DiTan hospital,understand the influence of the short-term large amounts of the hormone to ANFH. The method include reviewing the cases the pelvis X ray and MRI to understand the situation of the patients and pathogenic factors, assessing the disease progress and the effect of severe prognosis systemly and objectively. Its importance of clinical early diagnosis and treatment and the prognosis for a reasonable assessment.Methods:Choose 327 patients treated in the case of SARS from 8 march to 31 june 2003 in Beijing DiTan hospital, diagnosis by the ministry of health in april 2003 for the prevention and control infectious atypical pneumonia guide, 29 cases to death, 66 cases lost. Practical investigation cases 232 example, male and female 95 137 cases. the average age 35.6, The average hormones usage 6906. 3mg hormones always (1200—28000mg), the average daily dose 368. 2mg (80—1020mg) time, the use of steroids average 40. 5d (14—63d), the impact of the time. (80mg d) 29. 8d (eight 52d). 41 case of SARS patients use herbal treatment that the average age at an average 32.8 . All the patients are given in several cases, the pelvis and MRI being examined. in accordance with such intervertebral.ARCO international association in accordance with the circulation of the association (research circulation osseou ARCO in short). Statistical analysis: a spss15.0 software. significant statistical analysis of standards for 0.05 (p < 0.05).).Results:Practical investigation sars cases 232 example, male 95 and female 137 cases, the age of (8-75 ) years, the average age of (35士9.2 ). Of 191 patient had been ill all received a heavy dose of hormones, include 72 male cases, 119 female cases,hormones use of intravenous dripping of the Sugar massive cortical hormone. It comes to 65 patient was discharged from the hip in 95 after 2-8 months,include the limp, hip, knee pain and the discomfort symptoms. the clinical diagnosis for ANFH. Male 29 cases,from20-60 years, female 36 cases,from21-52 years, One-tailed: 36 example of 17 left 19 right.. Double side : 29 cases. of 33 cases accompanied by a femoral head collapsed. The average age is 35.6 year, the average usage 6906. 3mg hormones always (1200—28000mg), the average daily dose 368. 2mg (80—1020mg) time, the use of steroids average 40. 5d (14—63d), the impact of the time( >80mg d) 29. 8d (8-52d).41 case of SARS patients use herbal treatment that the average age at an average 32.8. 26.3 days in hospital ,without femoral head necrosis detected.Anatomy:ANFH of SARS patients on the short-term application of the hormone treatment heavy dose of medicine after 2-8months. Average rate of necrosis 34.0%, 50.8% collapsed. Use of steroids, a total of the application of the time, daily maximum impact of the time and therapy, have direct contact to the ANFH group. One of the greatest effect of steroids for accumulation and hormones were added to the application usage dates and total volume of the hormone. Hormones cause of the average size of erythrocytes increased have relevance with ANFH. |
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