The Study Of The Association Of Resting Heart Rate And Dibetic Nephropathy

Objective:To observe the resting heart rate and microalbuminuria in patients with type 2 diabetes. To study the association of resting heart rate and microalbuminuria. To investigate the promotion of resting heart rate on kidney damage in patients with type 2 diabetes.Methods:77 patients with type 2 diabetes who were diagnosed according to the diabetes diagnostic criteria were selected in out-patient clinic of our hospital. The criteria was adopted in china in 1999 by the American Diabetes Association (ADA) requirements. That was the fasting blood glucose is more than 7.0 mmol/L. At the same time, 45 normal cases were selected in physical examination center of our hospital. All the objects were excluded if they had complications like primary hypertension, thyroid disease, acute infections, primary kidney and ureter disease, et al. All patients were newly diagnosed or stopped drugs that affected heart rate more than 5 days. The information contained the duration of diabetes, gender, body mass index, fasting blood glucose and resting heart rate, et al. All date was analyzed in SPSS 13.0. All statistical tests were two sided withαof 0.05.Results:(1) There were significant differences between diabetic group and the control group in BMI, MAU, Ccr, BUN, glucose, TC, SBP, DBP(P<0.05).(2) There were significant differences between diabetic group and the control group in RHR. (3) The lever of MAU was correlated with diabetic duration, BP, RHR, Ccr; According to regression analysis, the longer duration of diabetes was, the greater value of MAU was. The faster of resting heart rate was.Conclusion:(1) Type 2 diabetic clients had faster RHR, which maybe associated with autonomy of the sympathetic nervous system dysfunction.(2) Resting heart rate is a damage factors on the development of damage on diabetic nephropathy.