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Clinical Study On Triple Therapy Of Knee Osteoarthritis

Posted on:2012-11-08Degree:MasterType:Thesis
Country:ChinaCandidate:L L WuFull Text:PDF
GTID:2214330368976591Subject:Orthopedics scientific
Abstract/Summary:PDF Full Text Request
ObjectiveInvestigate and compare the triple therapy (joints flushing, injection of hyaluronic acid, herbal fumigation) with intra-articular injection of hyaluronate clearance in the treatment of knee osteoarthritis efficacy, and guide clinical treatment.Methods:All cases are from 2009.12-2010.2 in the Orthopedics Department of Chinese Medicine Hospital in Hubei Province, Sports Department of Luoyang Orthopedics-Raumatological Hospital, according to cases of diagnostic criteria, inclusion criteria and excluded patients specimens, selected 60 patients (single Knee 50, double knees 10) were randomly divided into two groups, the treatment group give joints flushing, articular injection of hyaluronic acid, herbal fumigation in turn, the control group give joints flushing, intra-articular injection of hyaluronic acid. Before treatment, respectively, to knee osteoarthritis severity index (ISOA) score, while patients blood, urine, then routine, liver and kidney function and ECG, taken weight-bearing knee is lateral X films, a reference to Kellgren Lawrence grading criteria, 9 cases in treatment groupⅠ,Ⅱgrade 16 cases,Ⅲgrade 5 patients, in the control group 11 cases of gradeⅠ,Ⅱgrade 15 cases,Ⅲgrade 4 cases (because of this trial will be a significant joint space narrowing, Severe sclerosis, there is a large number of osteophytes or joint connection between the bone bridge formation was ankylosis as exclusion criteria, so the observations were not included in the first observation of the object class IV) 30 days,180 days after treatment, giving ISOA Score and clinical efficacy evaluation, and analysis with SPSS16.0. Two groups of gender, age and X-ray showed no significant differenceResults30 days after treatment,180 days after treatment clinical score were performed ISOA efficacy evaluation, and statistical analysis to be1. Statistics 30 days after treatmentThere is a significant difference between the two groups 30 days after treatment than before treatment ISOA scores, P<0.01. ISOA score after 30 days treatment, the treatment group and control group no significant difference, P> 0.05.2 Statistics 180 days after treatment2. 1Treatment group 30 cases, ISOA scores before treatment were significantly different compared, P<0.01. Clinical evaluation, excellent in 2 cases, good in 15 cases, fair in 13 cases, and poor 0 cases,56% excellent and good rate.2.2Control group of 30 patients, ISOA scores before treatment were significantly different compared, P<0.01. Evaluation of clinical efficacy were excellent in 1 case, good in 8 cases, fair in 19 cases, poor in 3 cases,30% good.2.3Treatment group and control group 180 days after treatment compared to the ISOA score and clinical therapeutic effect was significant difference.Conclusion:From the clinical treatment found that arthroscopic clean-up and treatment of intra-articular injection of hyaluronic acid knee osteoarthritis, effective and rapid, significant clinical improvement, but continued to work no well; triple therapy (debridement under arthroscopy, articular hyaluronic acid Injection, herbal fumigation) in the treatment of knee osteoarthritis in clinical symptoms and side effects are more advantages of consolidation. Description of Chinese medicine plays a important role to consolidate the treatment of knee osteoarthritis and fumigation efficacy. We believe that triple therapy (joints flushing, articular injection of hyaluronic acid, herbal fumigation) on the early and mid-term knee osteoarthritis have a certain effect, to improve the quality of life of patients, is worthy of clinical...
Keywords/Search Tags:Knee osteoarthritis, Arthroscopy, Hyalmoniac Acid, Herbal fumigation
PDF Full Text Request
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