The Analysis Of C Reactive Protein Leves In Preeclampsia And Eclampsia

Objectives The research through testing pregnant women during pregnancy changes of CRP levels, to investigate the incidence relationship between CRP levels of preeclampsia and eclampsia, meanwhile also discussed the CRP as preeclamia and eclampsia whether can predict indicators. Early prevention of diseases and improve maternal and child survival quality surrounded a certain significance.Methods We collected informations from Qin Huangdao Maternal and Child Health Hospital Obstetrics to antenatal examinationc and by Pregnant after 12 weeks in our delivery of pregnant women 1949 cases, who were evaluated from October 2009 to December 2010.In all respondents appear in patients with preeclampsia and eclampsia 102 cases as the case group; From the survey objects not occurring preeclampsia and eclampsia randomly selected the 120 cases of pregnant women as control group.Taking the self-made questionnaire, two groups of patients for investigation. After data arrangement with EXCEL the establishment of database,analyzed with the software SPSS13.0 analysis T Test, Crosstabs, One-Way ANOVA and Bivariate.Results 1.The case group and the control group in the generally comparison results display, two groups at the ages and cultural degree the difference was statistically significant (P<0.05); Pregnant number and abortion the difference was statistically significant (P<0.05);Family history had no statistically difference (P>0.05).2.In the first production inspection,two groups at the ages, BMI,MAP and Gestational age of production inspection had no statistically difference (P> 0.05).3.In the first production inspection, the case group CRP level was (3.49±1.31) and the control group was (3.33±1.35), and there was no statistically difference (P>0.05).Stratified analysis about Pregnant number and abortion the CRP levels had no statistically difference (P>0.05).4.In the first production inspection, along with the gestational weeks increase, the CRP levels rise more, the difference was statistically significant (F=10.678,P<0.001).5.In the childbirth, two groups at BMI, MAP and gestational weeks the difference was statistically significant (P<0.05).6.In the childbirth, the case group CRP levels higher than the control group,that was(27.00±20.55 vs 8.30±1.33),the difference was statistically significant (P<0.001).The CRP levels of Stratified analysis about Pregnant number and abortion difference was statistically significant (P<0.05).7.In the childbirth,Each groups along with the gestational weeks increase, the CRP levels rise more, the difference was statistically significant (F=25.934,P<0.05).8.In the childbirth, the CRP levels related to Pregnancy weight gain weight and mean artery pressure(P<0.05).9.In the childbirth, the CRP levels related to Urinary protein,renal function and liver function(P<0.05).Conclusions1.The early stages of pregnancy, the CRP levels in the case group and the control group had no statistically difference;2.Different gestational age at different levels of CRP, along with increased gestational weeks;3.In the childbirth, the CRP levels higher most in preeclamia and eclampsia;4.In the childbirth, the CRP levels higher with the increase of illness severity.