| Objective Analyze the prognostic factors for multiple myeloma(multiple myeloma,MM).Methods Collected from August 2002 to July 2009 in Ningxia Medical University Hospital diagnosed cases of MM patients information on the relevant data collation, analysis.Result 1.Younger than 60 years survival of patients older than 60 years than in patients with longer survival.2. Male and female survival of MM patients were statistically no significant difference.3. Hemoglobin greater than 100g / L survival of MM patients with hemoglobin less than or equal than 100g / L in MM patients with longer survival.4. Normal platelet survival in MM patients with reduced platelet survival in MM patients over a long period.5. Renal survival in patients with normal renal function compared with a longer survival in patients with damage.6. Survival of MM patients without bone damage is longer than survival of MM patients with bone damage.7. Plasma cell percentage less than 15% survival of MM patients with plasma cell percentage of 15% survival of MM patients were statistically no significant difference.8. IgG level of less than 70g / L Patients with shorter survival compared to IgG levels greater than 70g / longer survival of patients, IgA level less than 50g / L Patients with shorter survival compared to IgA levels greater than 50g / L in patients with longer survival.9. Albumin in patients with normal albumin decreased survival compared to patients with longer survival.10. The higher the level ofβ2-microglobulin in patients with shorter survival.11. Normal LDH in MM patients with LDH increased survival compared to patients with longer survival.12. Logistic regression analysis showed that age more than 60 years of age, thrombocytopenia, bone destruction,β2-MG> 5.5 mg / L, albumin reduction is independent of MM survival factors.13.VAD and thalidomide with chemotherapy Patients with longer survival compared to chemotherapy alone in patients with VAD .Conclusion 1.More than 60 years of age is a poor prognosis in multiple myeloma one of the factors, Gender has no relationship with the prognosis.2. Anemia, thrombocytopenia, renal damage, bone destruction, M-protein levels high, albumin reduced,β2-microglobulin increased lactate dehydrogenase were higher in patients with poor prognosis multiple myeloma and related factors,and more than 60 years of age, thrombocytopenia, bone destruction,β2-MG> 5.5 mg / L, albumin reduction is independent of MM survival factors. 3. VAD and thalidomide with chemotherapy Patients with longer survival compared to chemotherapy alone in patients with VAD . |
