To Investigate The Clinical Effects Of Jingzhuibing Electuary In Vertebral Artery Type Cervical Spondylopathy And Evaluate Its Mechanisms.

Objective: To investigate clinical effects of JINGZHUIBING electuary in vertebral artery type cervical spondylopathy with hyperactivity of liver-yang and evaluate its mechanisms.Method: Sixty patients with vertebral artery type cervical spondylopathy with hyperactivity of liver-yang were randomly divided into two groups: control group (30 cases)and experimental group (30 cases). Patients in control group were treated with Jingfukang granules, and patients in experimental group were treated with JINGZHUIBING electuary. Effective rate, scores of vertebral artery type cervical spondylopathy, plasma endothelin (ET)-1,serum nitric oxide (NO), plasma atrial natriuretic peptide (ANP),status of hemorrheology and hemodynamics were determined.Result: The effective rate in experiment was 86.67%,which was higher than that in control group(70%)(P<0.05). After treatment, scores of vertigo, tinnitus, neck pain, stiff neck , tenderness of neck, serum NO,SV and DV in experimental group were significantly higher than in control group (P<0.05), while plasma ET-1,ANP, BVH,BVL,PV,HCT,Fib,RI and PI were significantly lower than in control group (P<0.05).Conclusion: JINGZHUIBING electuary can effectively improve status of hemorrheology and hemodynamics, increase serum NO and inhibit plasma ET-1 and ANP. Its clinical effects is satisfactory...