| Objective:Observe the clinical effect of WenJing HuaYu ZhiTong Method to Cold blood stasis type of endometriosis patients with dysmenorrheal,and objectively and realisticly evaluate its efficacy.Methods:From the point of view of the Basic Theory of TCM, combined with modern medical testing technology,45 patients who belong to the type of cold blood stasis of endometriosis with dysmenorrhea were randomly divided into the treatment group and the control group by te ratio of 2:1, the treatment group is treated by WenJing HuaYu ZhiTong Method and the control group is treated by Tongjingbao Keli. Both groups were treated for 3 monthes.Observing the symptoms of dysmenorrhea,the signs of Gynecological Examining,the results of B-mode ultrasound and the situation of CA125 and anti-endometrial antibodies before and after treatment,and statistically compairing them.Finally,evaluating the clinical effect of WenJing HuaYu ZhiTong Method to Cold blood stasis type of endometriosis patients with dysmenorrhea.Results:Treatment group and control group both can improve their clinical manifestations, treatment groups:cure rate was 0.00 percent, markedly effective rate was 3.33 precent, efficiency was 83.33 percent, inefficiency was 13.33 precent,and the total effective rate was 86.67%; control group:cure rate was 0.00 percent, markedly effective rate was 0.00 precent, efficiency was 53.33 precent, inefficiency was 46.67 precent, and the total effiective rate was 53.33 precent. Through cheeckout, P<0.05, the result is that the efficacy of improving their clinica manifestations the treatment group was superior to the control group.Both groups can improve their Dysmenorrhea symptoms, treatment group:cure rate was 0.00 precent, markedly effective rate was 3.33 precent, efficiency was 90.00 precent, inefficiency was 6.67 precent,and the total efficiency was 93.33 precent;control group:cure rate was 0.00 precent, markedly effective rate was 0.00 precent,efficiency was 60.00 precent, inefficiency was 40.00 precent,and the total effective rate was 60.00 precent, Through cheeckout,P<0.05, the result was treatment group showed the superior effect of improving the symptoms of dysmenorrhea than the control group.The Chinese clinical symptoms of patients in both groups were improved, treatment group:cure rate was 0.00 precent,markedly effective rate was 3.33 precent, effective rate was 90.00 precent, ineffective rate was 6.67precent,and the total efficiency was 93.33 precent;control group:cure rate was 0.00 precent, markedly effective rate was 0.00 precent, efficiency was 60.00 precent, inefficiency was 40.00 precent, and the total efficiency was 60.00 precent. Through cheeckout, P<0.05, the resualt was that the efficacy of improving their Chinese clincal symptoms the treatment group was superior than the control group.Both groups could singnificantly decrease their symptom scores after treatment,and the contrast differences between the two groups before and after treatment there is obviously a significant (P<0.01), and that suggesting that the role of symptom improvement of the treatment group significantly better than the control group.After treatment, the size of the pelvic cysts (average diameter line) in the treatment group was significantly reduced and the gynecological inspection points was also decreased significantly,the difference was statistically significant (P<0.01).but in the control group, the size of pelvic cysts was not obviously reduced and the gynecological inspection points is not lower after treatment,the difference was not significant (P> 0.05).Both groups comparing the contrast difference before and after treatment was statistically significantly (P<0.01), indicating that the effect of reducing the size of the treatment pelvic cysts and improving signs of pelvic area the treatment group was effectiver than the control group.The level of CA125 was significantly decreased in both groups after treatment,and the differences were statistically significant (P<0.01). And the contrast differences between the two groups before and after treatment there is obviously a significant (P<0.01),suggesting that the effect of reducing the level of CA125 the treatment group was greater than the control group.the treatment group and the control group could improve the stasis of EmAb.In the treatment group the effecive rate was 87.50 precent,and in the control group the effective rate was was 37.50 precent,which is indicating that the efficacy of the treatment group was significantly better. During the treatment,both of the two groups were no adverse reactions.Conclusion:WenJin HuaYu Method can relieve dysmenorrhea and Chinese clinical symptoms; can improve pelvic blood circulation, reduce or dissipate the pelvic cysts and ectopic endometrial nodule; and also can improve the immune function, reduce the CA125 levels and suppress the autoimmunity. |
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