The Mechanism Discussion Of Nourish Qi-Promote Water-Activate Blood Law To Treat Nephrotic Syndrome

Nephrotic syndrome belongs to moisture disease category in《Jingui》,which values the relationships in QI,Blood and Water. The water in human body's metabolism depends on viscera gasification. If visceral functions wake or disorder, Qi can't carry water, the water deteriorates to form moisture disease. So does the Nephrotic syndrome, as the main characteristic with edema disease. Qi diseases cause blood diseases, blood disfluency causes water, water disfluency causes blood diseases, so there are fengshui,pishui,zhengshui,shishui,huanghan five types by Yinyangbiaoli; xinshui,ganshui,feishui,pishui,shenshi by five zang-organs; and the blood phase,the qi phase,moisture by the relationship in qi,blood and water.Based on the Nephrotic syndrome's clinical conditions, according to TCM syndrome differentiation, especially the theory of qi -blood-water treated together in《Jingui yaolue》, this paper proposes the treatment principle of nourish qi-promote water-activate blood to Nephrotic syndrome patients, nourish qi majors in replenish the spleen-qi and tonifying the kidney-qi. According to the clinical experience, choices milkvetch root, asiabell/ dried rehmannia root/ pulp of dogwood fruit/ chinese yam/indian bread/ alismatis rhizome/ moutan bark/ parched white atractylodes rhizome/mulberry bark/ areca peel/ tangerine peel/chinese waxgourd peel/ leonurus heterophyllus/ lycopus herb to make up nourish qi- detumescent decoction. In this decoction, milkvetch root/ asiabell/ chinese yam/ parched white atractylodes rhizome/ indian bread strengthen the spleen and replenish qi; dried rehmannia root/ pulp of dogwood fruit/ chinese yam tonify the kidney-qi,;mulberry bark/ areca peel/ tangerine peel/chinese waxgourd peel are good at the pishui treatment, diuresis-promoting and detumescence; leonurus heterophyllus/ lycopus herb can activate blood and diuresis-promoting. On the clinical treatment of Nephrotic syndrome, especially when hormone therapy was not good, this decoction had satisfied results at abating symptom/ eliminating Upro/ lowering blood pressure and other aspects."Nourish qi-promote water-activate blood law"is the basic rule to treat Nephrotic syndrome, but because of patients'constitutional difference and pathologic changes'difference, the clinical conditions are different, so the doctors have to modify dosage according to differentiation.