The Research Of Homocysteine In Coronary Artery Stenosis

Objective To discuss the predictive value of Homocysteine in coronary artery stenosis.Methods 81 subjects who underwent coronary angiography from Affiliated hospital of Qinghai University were recruited in this study.,Cases(n=57) with 75% stenosis in at least one of the three coronary vessels were angiographically defined as having coronary heart disease (CHD).Subjects (n=24)had 0% stenosis in all the three coronary vessels were considered as controls.CHD cases were divided into single vessel (n=34) and multi-vessel group (n=23). Plasma homocysteine was measured within 1 week before angiography in all subjects.Results Mean plasma homocysteine level was significantly higher in coronary patients than in controls [p<0.05] .Homocysteine level in the single vessel group or multi-vessel group were significantly higher compared with that in the controls [p<0.05]. The level of homocysteine in the multi-vessel group tended to be slightly higher as compared with that in the single group, while the difference was statistically insignificant (P>0.05).Conclusion Homocysteine level is elevated in patients with coronary heart disease.The high level of blood Hcy is a vital risk factor and it's an impoirtant means for preventing and treating the coronary heart disease...