The Relationship Among Heart Function, Pulmonary Arterial Pressure And ECG Indices In Patients With Coronary Heart Disease

Objective:To study the relationship between heart function and pulmonary arterial pressure (PAP), ECG indices in patients in coronary heart disease (CHD).Methods:According to NYHA classification,151 patients who were inpatiented in our hospital were classified with group A(Ⅰ,Ⅱ), group B(Ⅲ), group C(Ⅳ), compare PAP, P dispersion (Pd), QT interval (QT), QT dispersion (QTd), Tpeak-Tend interval (Tpe) and corrected QT (QTc), corrected QTd (QTcd), corrected Tp-e (Tpec) among three groups, and analyzed of the correlation between Pd and LAD, QTd and LVEDD, QTcd and LVEDD, Pd and QTd respectively.Results:①The value of Pd of patients of group A, group B, group C were 35.10±0.99ms,56.94±9.18ms,68.87±8.63ms respectively, the difference reached statistical significance (p<0.05), The value of LAD of patients of group A, group B, group C were 38.55±7.80mm,45.20±6.47mm,48.48±5.29mm respectively, the difference reached statistical significance (p<0.05), Spearman rank correlation test showed that the value of Pd was positively and statistically correlated with the value of LAD(r=0.368,P<0.05).②The values of QT/QTc and QTd/QTcd of patients were inrceased gradually and significantly with the deterioration of heart function in group B vs group A, group C vs group B (QT:423±42ms,448±35ms,473±35ms, P<0.05; QTc: 453±30ms,487±17ms,508±27ms, P<0.05; QTd:55±13ms,78±15ms,92±15ms, p<0.05; QTcd:59±15ms,90±16ms,101±18ms, P<0.05), The values of LVEDD of patients were inrceased gradually and significantly with the deterioration of heart function in group B vs group A, group C vs group B (47.81±6.26mm, 55.54±6.10mm,63.48±7.63mm, P<0.05).Spearman rank correlation test showed that the values of QTd and QTcd were positively and statistically correlated with the value of LVEED(r=0.602, P<0.05, r=0.610, P<0.05 respectively).③The value of Tpe and Tpec of patients of group C were significantly enhanced with that of group B and group A (Tpe:85.59±10.66ms,99.00±12.76ms, 112.39±9.52ms, P<0.05; Tec:96.20±2.42ms,106.67±20.59ms,120.77±13.76ms, P<0.05). ④The value of PAP of patients of group A, group B, group C were 23.88±6.07mmHg,43.29±13.47mmHg,51.56±10.65mmHg respectively, the difference reached statistical significance (p<0.05).⑤Spearman rank correlation test also showed that the value of Pd was positively and statistically correlated with the value of QTd(r=0.698, P<0.05). Conclusion:①With the deterioration of heart function in CHD patients, Pd is enhanced, the risk that patients suffer from atrial fibrillation is increasing, the value of Pd was statistically significantly related to the value of LAD.②With the deterioration of heart function in CHD patients, QT, QTc, QTd and QTcd are enhanced, the patients with heart failure are more likely to suffer from malignant cardiac arrhythmia, the values of QTd and QTcd were statistically significantly related to the value of LVEDD.③With the deterioration of heart function in CHD patients, Tpe, Tpec are enhanced, the patients with heart failure are more likely to suffer from malignant cardiac arrhythmia.④With the deterioration of heart function in CHD patients, PAP is inceasing.⑤The value of Pd was statistically significantly related to the value of QTd.