Study Of Relationship Between Xinjiang Uygur And Han Elderly Mild Cognitive Impairment And Plasmahomcyteine Levels

Objectives:the purpose of this study was investigate the relationship between Uygur,Han elderly mild cognitive impairment (MCI) plasma homocysteine(Hcy) levels,at the same time study of MCI other relivant factors。method:To the Xinjiang Uygur and Han population of≥60-year-old resident of epidemiological investigation, according to the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders Fourth Edition Revised Edition (DSM-IV) in the clinical diagnostic criteria for MCI diagnosis of MCI patients418. A case-control study case group by age group were randomly selected 1:2 ratio300. Results:1.the Uygur,Han and Uygur,Han tow ethinc MCL group plasma Hey levels comparition between the control group, there was significant difference between them (p＜0.001).2.comparition of Uygur,Han tow ethinc MCI groups plasma Hey levels and different age,there was significant difference between them (P>0.001)。3.Single factor analysis manifest:hypertension,diabetes,hyperlipidemia,smoking Htcy have statistical differences with MCI(P<0.05),while sex and nationality have not statistical differences with MCI (P>0.05); the logistic regression analysis showed:hypertension,diabetes,hyperlipidemia,smoking Htcy may increase the risk to MCI. Htcy is more risk than other factors (OR=1.162,P<0.05).Conclusion: 1.the plasma Hcy levels have closely relationship MCI。2.plasma Hcy levels gradually increased along with the MCIpatients ages.3. Hhcy is a independent risk factors of MCI.