Key Gene Pathways Analysis Of Canine Dilated Cardiomyopathy Based On Gene Set Enrichment Analysis

Canine Dilated Cardiomyopathy is a common disease characterizedby progressive loss of myocardial systolic function and eccemtric doilation.Despite its relatively high prevalence, the molecular mechanisms of thisdisease are poorly understood. In this study, the DCM expression chip datain the NCBI's GEO database were analyzed by gene set enrichmentanalysis (GSEA). A total of4gene pathways and the15significantlyupregulated GO were found. These significant gene sets can be used ascandidate pathways of canine DCM, and lay the foundation for furtherearly diagnosis, prevention and personalized treatment.