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Chinese Medicine Reduce The Embolization Due To The Toxicity Of Clinical Research,

Posted on:2011-02-06Degree:MasterType:Thesis
Country:ChinaCandidate:J R LiuFull Text:PDF
GTID:2204360305972504Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
In this paper, Summarize the past ten years Clinical Research, Inclued Reduce embolism syndrome, Protection of liver function, Reduce bone marrow suppression and Immune dysfunction. At Present the Mainly Non-surgical treatment of Advanced advanced HCC is chemotherapy and Transcathetery hepatic Arterial Chemoembolization (TACE).,but after interventional treatment prone to embolization syndrome, as well as the Adverse reactions such as Decreased immune function, Bone marrow suppression, Liver damage, etc. Caused by the chemotherapy drugs. theTCM can reduce adverse reactions follow the Treatment principles that Protect the" qi", cover the spleen and liver, Enhance blood circulation,lower heat and Detoxication.Objective:Observe the effects of TCM in reducing the adverse reactions of TACE to advanced HCC in clinical efficacy.Method:The Experiment is a randomized, placebo controlled study.120 cases met the inclusion criteria of cases, Will be randomly divided into experimental group (traditional Chinese medicine combined with TACE group) 60 cases and the control group (only TACE group) 60 cases. Observed after TACE, the blood cell analysis,hepatic function, and clinical situation of two groups of patients. And the collected data use the statistical analysis to compared and analyzed.Resulta:By comparing the scoring on varying degrees of adverse reactions, the hemoglobin, white blood cells, alanine aminotransferase, constipation, drug fever, non-cancer pain, these six points of the two groups through statistical analysis have statistically significant difference,P<0.05. the platelets, nausea, vomiting, diarrhea,these three points of the two groups through statistical analysis do not have statistically significant difference,P>0.05. Total sum of the two groups, comparing the results between groups, P<0.01, there are very significant differences, with clear statistical significance.Conclusion:The TCM have significant effects in reducing the adverse reactions of TACEto advanced HCC. In particular, in reducing the reactions on hemoglobin, white blood cells, alanine aminotransferase, after TACE. Curative effect in the side on Reduce constipation, drug fever, non-cancer causing pain.
Keywords/Search Tags:Adverse reactions, TACE, TCM
PDF Full Text Request
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