| Background:Pigmented pretibial patches (PPP) is an irregularly shaped lesions, atrophy of the pigmented spots. It was reported as the most common skin manifestations of diabetes. The reported incidence rate of PPP is 15% to 50%. Now, it is considered the basic pathological factor of PPP is microangiopathy of skin on the nutritional disorders, then due to minor trauma or caused by external factors to stimulate repair response. In TCM theory it is believed that this disease is due to disharmony between qi and blood, collaterals barrier and the skin caused by loss of support."Have underlying diseases, there will be performance of external"PPP is a kind of dermal symptoms in diabetic patients, thus it can reflect the general condition of patients. Therefore, to study the would provide a reference for clinicians institute overall treatment programs for diabetes patients.Purpose:To inquiry TCM syndrome features of PPP patients could provide evidence of diagnosis and treatment for diabetes patients.Methods:Retrospective study 231 cases who got type 2 diabetes, according to whether associated with PPP, they were divided into two groups: observation group (with spots) and control group (no spot).159 cases in observed group,72 patients in control group.All patients were recorded the skin of lower extremity, sensation and toe nails, etc. In accordance with the Association of Chinese Medicine Diabetes Branch established criteria (promulgated in 1992) for classification, according to clinical symptoms, tongue, pulse classification type, the difference between the two groups were compared. By SPSS17.0 statistical software to analyze the results, measurement data for x±S, count data was used to compare percentages between groups x2test.Results:1. There were ten types of TCM syndromes in the observation group and the order were:blood stasis in 110 cases (69%),84 cases of qi deficiency (53%), kidney deficiency syndrome in 69 cases (43%), Yang Deficiency of 68 cases (43%), liver blood deficiency 58 cases (36%), Qi Yu of 58 patients (36%), humidity of 58 patients (36%), Yin deficiency syndrome in 38 cases (24%), hot of 30 cases (19%), dampness in 19 cases (12%);2. There were differences between the two groups in incidence rates of yang deficiency, kidney deficiency syndrome, liver blood deficiency, blood stasis, Qi Yu certificates and damp statistical;3. The incidence rate of two-associated syndromes were Qi deficiency and blood stasis were 56 cases (35%), kidney deficiency and blood stasis were 49 cases (30%),47 cases of yang deficiency blood stasis (47%), liver deficiency and blood stasis in 44 (28%), qi stagnation (Yu) Blood stasis (26%);4. The observed group compared with the control group,"lower extremities cool,""dry skin lower limb","toe a thicker and darker"and there were significant difference in the incidence rate;5. The observation group and control group differenced in the proportions of men and women;6. In observed group, the different age groups, different disease course in patients with tibial number and color of pigmented spots was no significant difference; the anterior tibial number of different pigmentation, color, different shades of the patient's age, history and medicine syndrome there was no significant difference.Conclusion:1. Blood stasis was the main syndrome of PPP, followed by the qi deficiency, kidney deficiency syndrome, yang deficiency, the liver blood deficiency, Qi blocking and dampness heat.2. The feature of TCM syndrome of PPP was mixed insufficiency and excessiveness syndromes. The order of incidence rate of main two-associated syndromes were:Qi insufficient and blood stasis syndrome.kidney deficiency and blood stasis, yang deficiency blood stasis, liver deficiency blood stasis, Qi and blood stasis.3. The observation group had higher incidences of yang deficiency, kidney deficiency syndrome, liver blood deficiency, blood stasis, Qi Yu and a higher damp-heat syndrome; other syndrome groups no difference in incidence.4. The observation group were more likely to have"lower extremities get cold,""dry skin lower limb","toe a thicker and darker,"and other symptoms.5. The male incidence of PPP was higher than in females. |
PDF Full Text Request