Yiqijiedu Tongluo Fang Clinical Studies Of Patients With Primary Biliary Cirrhosis

Primary biliary cirrhosis(PBC) is an unexplained chronic inflammatory and cholestatic liver diseases, which belongs to autoimmune disease. Autoimmune liver diseases include autoimmune hepatitis (AIH), primary biliary cirrhosis and sclerosing cholangitis (PSC). Comprehensive information from the literature in which primary biliary cirrhosis take a higher proportion. The disease occurs mainly in middle-aged women, often associates with extrahepatic specific autoimmune diseases such as sjogren's syndrome, rheumatoid arthritis and so on.The main pathological features include damage of small bile ducts, inflammation of the portal area, cholestasis and liver fibrosis, and may eventually progress to cirrhosis and liver failure. At present the nosogenesis of primary biliary cirrhosis has not yet fully understood. Domestic and foreign scholars in-depth study of its pathogenesis and has made great progress from genetic susceptibility, immune system and infection and chemical substances and so many angles. With its incidence increased year by year, it had serious affected on people's quality of life and health. Therefore, early diagnosis and timely treatment, blocking the pathological process of liver cirrhosis can take great significance in improving the patients quality of life and prolong life.Yi Qi Jie Du Tong Luo Fang is an experience medical prescription of mytutor whose name is Guangfu Xu. Mang years of clinical observation shows that the methods and ideas fit the pathogenesis of chronic liver disease.It can resist hepatic fibrosis remarkably. To investigate the therapeutic efficacy of Yi QiJie Du Tong Luo Fang on primary biliary cirrhosis and its mechanism of action, this subject use Yi Qi Jie Du Tong Luo Fang treatment 30 patients of primary biliary cirrhosis. The results that comparing before and after treatment indicate that the therapy group effective rates were 93.4%.It was also found that the improvement of manifestation, hepatic function, cholestasis and B-mode ultrasonic of the therapy group was significantly.In conclusion, Yi Qi Jie Du Tong Luo Fang can prevents the progress of PBC evidently, and it has not toxic side effects, also is not expensive. It is worth considering as a promising Chinese material medica for the treatment of PBC.