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Clinical Observation Of The Of Periodontal Elimination Of Oral Treatment Of Periodontitis

Posted on:2010-02-17Degree:MasterType:Thesis
Country:ChinaCandidate:L N QuFull Text:PDF
GTID:2204360275478769Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Periodontitis refers to occur in the chronic progressive teeth support organizational destructive diseases。The periodontitis partial main performance is inflamed gingival bleeding,the formation of periodontal pocket,overflow periodontal abscess,alveolar bone absorption and loose tooth.Modern medicine believe that,on the one hand,the invasion from specific bacteria found in plaque and their production to host are the initial factors of periodontal disease;on the other hand,the occurrence and development of periodontal disease are impacted and accommodated by the general factors,such as heredity, immunity,systemic diseases,and endocrine networks.But to treat general factors, modern medicine uses antibiotics.It leads to dysfunction of patients' digestion system,and damage of liver and kidney function.Based on the TCM theory,we develop YZXL Chinese Pattern Herb, through organic wholeness and syndrome differentiation.It can clear stomach fire, nourishing fire and cooling blood,also tonifing kidney and making teeth strong. YZXL is pure preparation of proprietary Chinese medicines to a simple drug,but has significant clinical efficacy,rich source of herbs,cheap and easy to take. After more than ten years of clinical application,clinical effects in patients with better,the subject of oral periodontal eliminate the efficacy and safety of in-depth, objective,scientific discussion,for the Chinese medicine treatment of periodontitis ideas to provide better treatment.Research Objects and MethodsResearch Objects:This study observed from July 2008 to December 2008, China Academy of Traditional Chinese Medicine Guang'an Men stomatological hospital out-patient clinical diagnosis of mild to moderate chronic periodontitis, the TCM diagnosis of the symptom of flaring up of stomach fire,the initial 42 patients studied,excluding off patients,41 cases were collected.All subjects signed informed consent,voluntary participation in this study.Research method:A randomized,parallel-controlled project is adopted in this study.42 patients with "flaring up of stomach fire" periodontitis,were divided two groups:the test-one were given"Yazhouxiao liquid",while the control-one were given "Huanglian Shangqing pill".A week later,the difference of curative effects between these two groups were evaluated by investigating the Points of periodontitis and the symptoms of TCM.The difference of security between them was estimated through comparing blood,rutine,urine rutine,hePatic function,kidney function and ECG.Build a data base according to all CRF forms,use the SPSS11.5 software to carry out statistic analysis,all of statistic test are bilateral test,check the standard a = 0.05. Adopt the t checkout,Chi-square test,Rank sum test,according to studying purpose and the data character.ResultThere was no statistical significance(P>0.05) on the difference of baseline information between test and control groups,which showed that there was comparability between them.After treatment,there was great improvement on symptoms of periodontitis and the symptoms of TCM in both groups,the difference between them has statistical significance.About peridontitis,the efficacy of YZXL was 66.67%,on syndrome of TCM,the efficancy of YZXL was 57.11%.During the whole experiment,there was no adverse drug reactions happened in "Yazhouxiao liquid "group,but in "Huanglian Shangqing pill" group there was a patient Mild diarrhea after taking the pill a day,not having handled,relieving by herself,already accomplished entire experiment process; other patients in "Huanglian Shangqing pill" group did not appear adverse drug reactionsAfter this randomized,parallel-controlled experiment,the result shows us that YZXL is better than HLSQP on treating gum bleeding and gum swollen,also on improving the syndrome of flaring up of stomach fire。Discussion1.As a common and frequently-occuring disease in oral cavity,periodontal disease is the main reason of tooth loss in adults.The complexity of its pathogenesis,there is no effective method to heal.This topic tight associate with clinical practice,apply atatistical method severity,Conducted a phaseⅡclinical observation of YZXL,Has certain Practicality.This topic Observe the clinical efficacy of YZXL on treating periodontitis belonging to the symptom of flaring up of stomach fire.And select Huanglianshangqing pill as a control drug to compare, observed Specific differences between the efficancy in the treatment of Periodontitis belonging to the symptom of flaring up of stomach fire.After the results of statistical analysis,the result shows us that YZXL is better than HLSQP on treating gum bleeding and gum swollen,also on improve the syndrome of flaring up of stomach fire。2.Observation of the subject drug"YZXL",With previous similar comparison of Proprietary Chinese medicine for treating periodontitis is characterized by the following:(1) Liquid formulations packaged,at present,there is no clinical oral liquid form of pure Chinese medicine for treating periodontitis,so YZXL will fill this blank of drug formulations.(2) YZXL is pure Traditional Chinese Medicine,Sugar-free,bitter tasting, diabetes who can not accept initial therapy can use YZXL.(3)Under the principle of clear stomach fire,nourishing fire and cooling blood,also tonifing kidney and making teeth strong,YZXL focus on the function of the host of adjustment disorder,regulation of host defense function,make up inadequacies of western medicine.(4)YZXL Composed of a simple drug,but has Significant clinical efficacy,rich source of herbs,Cheap and easy to take.More applicable for patients who can not take western medicine because of digestive disease.3.This topic,it is just need to serve patients.Test results show that YZXL is efficacious and safe.This treatment of periodontitis using TCM method just provide a better basis for clinical trials.Chinese medicine research need to improve the host immune system to provide better clinical guidance.Western medicine carried out initial treatment,at the same time,using antimicrobial agents, In order to ease inflammation.But to enhance the capacity of the host systemic immune regulation,western medicine is often unsatisfactory,so we should play the advantages of Chinese medicine,based on theory about"the concept of integrity"and "the treatment on the basis of syndrome differentiation",improve the host immune system,reconcile the yin and yang,to stimulate a patient's own defense mechanism,improve their own immunity,making the body upright, adequate strength.4.As the pilot of financial constraints,in this study,there are still inadequacies, such as,select the number of cases less,lack of sufficient sample size.We should further improve the study in the future.
Keywords/Search Tags:Yazhouxiao liquid, periodontitis, curative effect, security
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