Coptis Pieces Processing Technology And Quality Control

Rhizoma Coptidis is a traditional Chinese medicine,attached to Ranunculaceae,a kind of rhizome of Coptis chinensis Franch or Coptis deltoidea C.Y.Cheng et Hsiao or Coptis teeta Wall.It is bitter in taste,tiny cold in medicinal properties.It can neutralize poison,rash down fire of moxibustion,clean up pyretic toxicity and arescent humid heat.The article overviews the processing and modem development,to illustrate the GAP of primary Rhizoma Coptidis and study systemly processing and quality standard.The paper formulate quality standard of Rhizoma Coptidis,HPLC method is utilized to determine the content of the fat,moreover distinguish by finger printing and ultravioletspectral lines.1 Processing technology studyingAccording to requirement of processing normalization and in order to improve clinicaliy effect,we deploy typical medicinal,Rhizoma Coptidis provided by growth depot of GAP Rhizoma Coptidis of Hubei province to select the best processing technology.The five alkaloid of Rhizoma Coptidis are all quartermary ammonium alkaloids,they solve in water easily.So select some alvin miltiorrhiza to sieve water processing,the content of salvianic acid,water and alcoholcomponents,total ash of different samples were determined standard.L₉(3⁴)orthogonal yayout was used to select the best water processing.i.e second water-adding amout,washing 2 times,sixty seconds every washing time.Incide alvin miltiorrhiza which is the best washing technique with dia-moistening and easy to cut as quality criteria.Incide junk to dry,then select the best drying technology.The iptinal procedure was set as follows: toasted 4 hours at the temprature of 60℃,two turning-over and loose.Last study on technology of stir-fry processing with wine.The best way is to stir-fry 6 minutes with 12.5%wine at the temperature of 170℃,then taken out and cooled down.2 Quality standard studyThe thin layer chromatography condition was founded to analysis the crud character and quality,the TLC method is special and reproducible.The ultravioletspectral lines method is also used to distinguish.The method is reproducible,easy,faster and exact.The method HPLC was establishes to determine the content of berberine.The result of this test is more exact,steady and easier.The HPLC method for the setting up the ghormatogram fingerprint of Rhizoma Coptidis and wine Rhizoma Coptidis was established.Through determining the chormatogram fingerprint,the method is faster and easier to distinguish them.The topic studies processing technology of Rhizoma Coptidis,sets up quantization index of technologial manufacture,this is profiting for mechanization manufacture. Meanwhile,to formulate quality criteria of Rhizoma Coptidis,upgrade the quality of Rhizoma Coptidis and its clinical curative effect.