Different Dose Fufangjiakang Piece Of Clinical Observation, Ease Of Subclinical Hyperthyroidism Curative Effect On Hyperthyroidism

1.Objective:Subclinical hyperthyroidism is a special type of hyperthyroidism, the clinical manifestations of concealment,easily overlooked.Subclinical hyperthyroidism due to the potential hazards,affect the health of patients, correctly handle the sub-clinical hyperthyroidism have important clinical significance.Through clinical trials research,observation compound different treatment of hyperthyroidism-the amount of Qiyinliangxu group of sub-clinical hyperthyroidism impactof the clinical efficacy and tapazole the control group, for further guidance lay the foundation for clinical use.2.Method:Reference to the Ministry of Health in 2002 promulgated the "Chinese medicine treatment of hyperthyroidism the new drug clinical study of the guiding principles",select Western medicine for diagnosis of subclinical hyperthyroidism,and in accordance with the treatment of hyperthyroidism in the process of remission in subclinical hyperthyroidism Stage,the dialectic of Chinese medicine for patients with type Qiyinliangxu 165 cases,patients will be randomized into four groups,each have one month of treatment for a total of three observation of treatment.In the administration before and after treatment every month TCM Syndrome observe its efficacy and serum free Triiodothyronine(FT₃),serum free thyroxine(FT₄)and serum thyroid stimulating hormone(TSH)value of the change.Meet the standards of this study in patients with a total of 165 cases,according to join the test sequence of numbers,were randomly divided into A,B,C,D four groups,namely Group A:Tablet-FuFangjiaKang low-dose group 6#/d;B Group: Tablet-FuFangjiaKang dose group 10#/d group;C Group:High-dose Tablet-FuFangjiaKang 15#/d group.Group D:tapazole-10 mg/d.Randomly assigned to the A,B,C,D group of a few cases were 42 cases,42 cases, 40 cases,41 cases.Group A:oral Tablet-FuFangjiaKang twice a day,once 3mg;B group:oral Tablet-FuFangjiaKang twice a day,once 5mg;C groups: oral Tablet-FuFangjiaKang a day three times,once 5mg;D groups:oral tapazole twice a day,once 5 mg.Each group for more than a month course of treatment,a total of three observation of treatment.In addition to provisions of the anti-drug hyperthyroidism compound in the treatment of hyperthyroidism,the observation period,abnormal liver function for two-fat biphenyl,and so Hugan,if interleukin below normal value,or interleukin drug benefit to blood hygiene,Vitamin B4,and so conventional as tachycardia,such as propranolol to control heart rate,as some elderly patients with osteoporosis to the music of calcium,and so on.3.Results:The clinical observation showed that:A,B,C,D Qiyinliangxu four groups of sub-clinical treatment of hyperthyroidism,four groups of patients with thyroid hormone levels are different degrees of improvement,three months after the resumption of normal patients in group A For 28.57%,B group was 57.14%,C group was 50.00%,D group was 36.59 percent.Laboratory effects of B,C group on superior efficacy in A,D group,P<0.05 there was a significant difference;chi-square test compared with group A and group B,B group is not only effective than group A,while in the treatment of The incidence of hyperthyroidism also significantly lower than in group A,P<0.05,a statistical significance compared with chi-square test B,C group,no difference in side effects P>0.05,but the group B in the treatment of hypothyroidism Rate is superior to Group C,P<0.05,a statistically significant;A,D There was no difference between the two groups,P>0.05 was not significant.A,B,C,D with four points in the syndrome signs were improved after treatment,P<0.05 statistically significant,the group showed no differences.Each group had symptoms improve after treatment,group B comparison group of palpitation and fatigue inability to improve the symptoms of these two is better than the other three groups(P<0.05).Safety Evaluation:The clinical observation during the group no adverse reaction occurred,suggesting that the clinical observation of the security of good.4.Conclusion:The observation results show that the Tablet-FuFangjiaKang daily volume of 10 sub-clinical hyperthyroidism treatment,the improvement of clinical symptoms and signs of resumption of TSH in both good effect, especially in improving the symptoms of weakness and fatigue palpitations, The effect of better and improve the quality of life of patients,reflected in the joint application of the advantages of Western medicine.However,because this clinical observation of cases of inadequate samples,observe a shorter time,it is inevitable there are insufficient,Tablet-FuFangjiaKang on subclinical hyperthyroidism pending further study of the effect of the observation,a reasonable clinical dose also need to be further Explored.