Clinical Efficacy Of The Treatment Of Blood Eyesight Party Control Of Primary Open-angle Glaucoma, The Optic Nerve Protection

Objective:To investigate the therapeutic effects of Huoxuemingmu Prescription(HXMMP)in the protective treatment of optic nerve,for the patients with primary open angle glaucoma controlled.Method:56patients were randomly divided into two groups, with 48 eyes of 28 patients in treating group treated by HXMMP, nutrient nerve drug and mixed preparation of energy,and 47 eyes of 28 patients in controlling group treated only by nutrient nerve drug and mixed preparation of energy.Meanwhile the indexes were detected included curative effect,visual field, pattern-VEP,CDFI and hemorheology before and after treating course.Results:The total effective rate was 66.7%in treating group,with 19 eyes significantly effective,13 eyes improved, 14 eyes stable and 2 eye ineffective.In contrast,it was only 21.3%in controlling group,with 2 eye significantly effective, 8 eyes improved,33 eyes stable and 4 eyes ineffective,and treating group being superior to controlling group(p＜0.05). When compared with that before treating course,average photosensitivity,PSV and EDV of OA,CRA and SPCA were all significantly higher in treating group after treating course (p＜0.05).Furthermore,there were alse significant differences in the same indexes between treating group and controlling group after treating course,with obviously higher in treating group(p＜0.05).When compared with that before treating course, average defect,RI of OA,CRA and SPCA,blood viscosity,plasma viscosity,HCT and fibrinogen were all significantly lower in treating group after treating course.Moreover,there were also significant differences in the same indexes between treating group and controlling group after treating course,with obviously lower in treating group(p＜0.05).There were no significant differences in LP₁₀₀and AP₁₀₀of treating group between before and after treating course,and the same result were observed between treating group and controlling group after treating course.Conclusion:HXMMP can enlarge visual field,elevate visual acuity and protect optic nerve owing to accelerating blood flow velocity,lowering vessel resistance,enhancing blood and oxygen quantity within eye bails,improving damaged, not dead,RGCs' recovery,speeding up normal RGCs' compensation and ameliorating axial flow transportation in the district of yellow spot.