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Hyperlipidemic Acute Pancreatitis Progress

Posted on:2009-11-17Degree:MasterType:Thesis
Country:ChinaCandidate:N SuFull Text:PDF
GTID:2204360245456941Subject:Integrative Medicine
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The incidence of acute pancreatitis (AP) has increased greatly, which does grievous bodily harm. Bsides bile duct stone, over-drink and over-eat, hyperlipemia is one of the main factors too. This article will discuss the mechanism and clinical characteristics of hyperlipidemic pancreatitis (HLP) and summarize the understanding of Chinese Traditional Medicine in AP.Percentage in Case reporting of acute pancreatitis concurring with hyperlipemic has difference in research, but mostly between 12% and 38%. The percentage of hyperlipidemic acute pancreatitis of all acute pancreatitis is from 6.9% to 12.6%. The relationship between hyperlipemia and acute pancreatitis can be concluded as (1)They are homologous;(2)AP leads to transient hyperlipemia;(3)HL leads and worsens AP. Lots of people think that AP can mildly increase TG,and the significant rise of TG can directly bring out AP. The mechanism of HLP is complex, HL affects pancreas secretion, induces microcirculate obstruction and damages pancreatic gland cell. HLP has some clinical characteristics as the rise of AMY is out of proportion to the seriousness of pacreatitis; organ failure will appear at the early stage; the pancreatic pseudocyst and abscess will appear at the late stage. At present the diagnosis of HLP mainly depends on case history and the level of TG when patients came to hospital. AP can be diagnosed as HLP when serum TG≥11.3mmol/L and eliminating the obstruction of biliary tract. It also can be diagnosed as HLP when 5.65mmol/L≤TG≤11.3mmol/L and chylemia. It can not be diagnosed as HLP when TG<5.65mmol/L. While conventional treatment of AP, we have better reduce TG down to 5.65mmol/L as soon as possible. Blood purification can reduce serum TG of severe patients; also block necrosis of pancreace and organ failure. Relapseis the character of HLP,which will be prevented by taking tibric acid and dietary intervention. Pancreatitis was known for many years in traditional Chinese medicine. In Chinese traditional medicine the anatomy position of pancreas is belong to spleen. Acute pancreatitis fit the"Epigastrium","Hypochondriac pain","Ge pain","Stomachache","Wei-Xing pain","Bei-xing pain"in Chinese medical symptoms. The position is about spleen, liver, gallbladder and stomach. Early stage of disease appears as Qlstagnation and Food Retention, or Stagnated heat in Liver, gallbladder, spleen and stomach. After its turn in to Heat Poison and at end stage will be weakness of spleen and stomach. Differentiation could accord organ differentiation or the six meridian syndrome differentiations. There are many reports about Chinese medical treating AP for good results.People have recognized HLP, but not taken it very serious. Diagnosis, treatment and pathology study of hyperlipemic pancreatitis need to be improved. Traditional Chinese medical differentiation of acute pancreatitis, and the effective Chinese medicine and ingredients should be systematized, that could shape treatment of AP in Chinese medical up to next stage. We will find a way to treat AP by combining Chinese traditional medicine and western medicine.
Keywords/Search Tags:Acute Pancreatitis, Hyperlipemia, Chinese Medicine
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