Hypoglycemic On The 1st Intervention Clinical Studies Of The Metabolic Syndrome

Metabolic syndrome is a series of metabolic abnormity whose core is insulin resistance, including obesity, hypertension, blood-fat abnormity, sugar tolerance abnormity. This disease has high incidence and been thought highly in clinic. This topic put importance on TCM research of insulin resistance, arranging and inducing different TCM learning standpoint, summing up the action mechanism and treatment regularity of treating on liver and stomach. We investigate that jiangtangyihao affect the insulin sensibility, weight, blood fat and insulin secretion phrase on clinic initially.This topic is on account of my advisor's long-term practical observation in clinical. We find that most patients of metabolic syndrome have hyperphagia and fat stage before they have MS. They often have restlessness and tantrum, fullness in chest and hypochondrium, polyphagia and hungry, yellowish or reddish urine, dry mouth, bitter taste of mouth , dry stool, red tongue with yellowish fur ,string and frequent or slide pulse in the early metaphase. The differentiation of symptoms and signs of TCM is hepar-gastric heat retention. Then we treat it from dispersing the depressed liver-energy,regulating the stomach ,ducing the heat. dispersing blood stasis and dredge collateral. We set up jiangtangyihao on the base of dachaihutang and didangtang in .Avandia is positive controlling group in this topic .We observe weight, waistline, abdomen circumference, blood sugar, insulin, insulin sensitivity index, blood-fat, symptom score of 57 MS cases from pretherapy and post-treatment. The result is jiangtangyihao has visible effect on blood sugar and blood fat abnormity of MS patients and can loose weight ,increase insulin sensitivity index, improve symptoms of hypochondrium, dry mouth, dry stool etc.The mechanism of Jiangtangyihao may concerned with loosing weight, decreasing waistline and abdomen circumference, improving blood fat disorder, increasing insulin sensitivity index. The concrete action mechanism should be investigated furtherly.