Experimental The Calamus The Acacia Granules Intervention Sleep Study

First ,backgroud and purposeInsomnia is one of somnipathies, which is high morbidity. People are not very clear for mechanism of sleep and insomnia now. Sleep is a higher nervous activity and proceeds voluntarily in CNS. Central nervous theory, body fluid theory and circadian rhythms periodicity theory are the three most important theories about sleep.In treatment of insomnia,west medicine can acquire certain effect,but there are lots of side effects by long-term usage.It's more less than gains.TCM has the special theory and means in dealing with diseases.There is a good effect in treatment of insomnia by TCM,moreover less side effect.For these reasons,this research chooses the past of spine date seed,which was used and researched for many years.We study insomnia by the experiments of ChangPuHeHuanChongji.We hope that our study can supply some methods and approaches to the therapy of insomnia .Second ,methodsThe review articles divide into four parts, modern medicine articles,ancient TCM articles, modern TCM clinic articles and experimental articles.Our experimental study is composed of four parts.Part 1, analyzing the variation of the content of 5-HT,5-HIAA,NA,DA of betweenbrain, brain stem by high performance liquid chromatogram(HPLC).In part 2,3 and 4,we divide male KM mice into four groups in order to observe mice different spontaneous activity and sleep. They are normal saline group, estazoam group,low dose ChangPuHeHuanChongJi,high dose ChangPuHeHuanChongJi.TCM has the sleep theory based on wide angle constructed by consciousness , entrails,function of meridian and QI-blood,and the relationship of each other.TCM correlates human body with the living condition and social circumstances and has lots of means to diagnose and treat.The TCM means to insomnia treatment concludes herbs , acupuncture,medicated-bath,massage,breathingexercise, psychotherapy , diet,music,etc.It is in the line with modern model of biology–psycho -social medicine.Third , resultsthe content of NE decreases in the estazom group and ChangPuHeHuanChongJi,but only the difference of the estazom group is significant(P<0.05).The content of 5-HIAA increases in the estazom group and ChangPuHeHuanChongJi group, but only the difference of the estazom group is significant(P<0.05). The content of 5-HT increases in estazom group and ChangPuHeHuanChongJi,but the difference in both of the groups isn't significant.The content of DA in estazom group and ChangPuHeHuanChongJi decreases ,but the difference...