| ObjectiveDiscuss the regulation of syndrome distribution of AS, establish the principal syndrome,and the important element to differentiate the principal syndrome. And approach the method concerning the research of TCM syndrome. MethodApply the cross-sectional study of clinical epidemiology, design the clinical questionnaire and fill in, acquire the data. And utilize SPSS 11.5 to finish statistical analysis. Discuss the regulation of syndrome distribution of AS as well as the relevant factors. Establish the main ingredient to differentiate the principal syndrome. Result1 The invasion feature. The AS effect the youth among 20 and 30 principally, the male more than the female. Which onste any of four seasons in the year, especially in the spring, summer. But it aggravates major in spring and winter. The initiatory syndrome mainly is soreness in lumbosacral or joints of limbs. And the peculiarity of the soreness mostly is stiff pain, vague pain, aching pain, pricking pain. 2 The clinical syndrome, high frequency syndrome: pain in the lumbosacral region, limited motion in the lumbar vertebrae region, stiff in the moring, pain in back, heavy sensation in limbs, aching and weakness in the loins and knees, pain which ia worsened at night. During the active stage, the syndrome from high frequency to low is: limited motion in the lumbar vertebrae region, pain in the lumbosacral region, stiff in the moring, pain in back, pain which ia worsened at night, heavy sensation in limbs, pain in hip. During the non-active stage, the sundrome by turns is: pain in the lumbosacral region, limited motion in the lumbar vertebrae region, stiff in the moring, pain in back, aching and weakness in the loins and knees, aversion to cold with preference for warmth, pain which ia worsened at night. 3 The regulation of syndrome distribution: as the investigation results showen:most cases display for compound syndromes.The main performance is two or three combinations,among which the two syndromes combinations are the most common ones. The basic syndrome mainly is: damp and heat blocken syndrome, syndrome of kidney yang asthenia, blood stasis syndrome. The most commom combination is damp and heat blocken syndrome combined with blood stasis syndrome, syndrome of kidney yang asthenia combined with blood stasis syndrome, which often appear in the active stage or non-active stage respectively. The later Combinationoccurs more often during the intermediate and later stage, which implys that with the desease development, the syndrome of kidney yang asthenia and blood stasis syndrome also tends to serious condition.4 Discuss with the important element to differentiate the principal syndrome of AS. the syndrome damp and heat blocken combined with blood stasis: there are more major clinical manifestations that were found though frequency analysis except the four main clinical appearance, including heavy sensation in limbs, pain in back, pain which ia worsened at night, pain in hip, dry mouth and hydrodipsia etc, picture of tongue including light-reddish or dull tongue, thin and yellow or thick and yellow tongue fur, slippery and taut pulse; It is the major element to differentiate syndrome that were found through Binary logistic regression, contains joints with redness, swelling, hot sensation pain, heavy sensation in limbs, pain in heel, humpback, thin and taut pulse. And judge the syndrome on prediction ratio 0.5 as critical point, the accurate rate is 88.1 %; the results through discriminant analysis imply that the major element to differentiate syndrome is joints with redness, swelling, hot sensation pain, heavy sensation in limbs, pain in heel, palpitation and flustered, humpback, slippery and taut pulse, and erect the Fisher's function, coincidence is 88.1 %, sensitivity is 77.3 %, specificity is 92.7 %, Kappa is 0.695. syndrome of kidney yang asthenia combined with blood stasis: there are more major clinical manifestations that were found though frequency analysis except the four main clinical appearance, including aching and weakness in the loins and knees, aversion to cold with preference for warmth, aggravates with cold and alleviates with warmth, pain in hip, pain which ia worsened at night etc, picture of tongue including light-reddish tongue, thin and white tongue fur, sunken and thin pulse; It is the major element to differentiate syndrome that were found through Binary logistic regression, contains aggravates with cold and alleviates with warmth, pain in heel, lassitude, aching and weakness in the loins and knees, thin and white or thin and yellow tongue. And judge the syndrome on prediction ratio 0.5 as critical point, the accurate rate is 83.5 %; the results through discriminant analysis imply that the major element to differentiate syndrome is limited motion in the lumbar vertebrae region, heavy sensation in limbs, aggravates with cold and alleviates with warmth, pain in heel, lassitude, aching and weakness in the loins and knees, thin and white tongue, and erect the Fisher's function, coincidence is 84.0 %, sensitivity is 67.8 %, specificity is 91.1%, Kappa is 0.609. Conclusion 1 It is the necessary tendency for TCM standardization to study for syndrome... |
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